Over the last decade, evidence has emerged to support a role for the antidiabetic drug
metformin in the prevention and treatment of cancer. In particular, recent studies …

Several molecules are being investigated for their ability to enhance the anti-tumor effect of
radiotherapy. The widely prescribed antidiabetic drug metformin has been suggested to …

Background Metformin, a primary treatment for diabetes mellitus (DM) patients, is associated
with improved outcomes for diabetic cancer patients fuelling further investigation on its …

Introduction: Metformin, the most widely used treatment for diabetes, is lethal to cancer cells
and increases in toxicity when used in combination with radiation. In addition to various …

Background: Nowadays, ionizing radiation is used for several applications in medicine,
industry, agriculture, and nuclear power generation. Besides the beneficial roles of ionizing …

Purpose Metformin is a key pharmaceutical for patients with diabetes mellitus (DM).
Metformin also can enhance tumor radiosensitivity in vitro and in vivo. Some retrospective …

Background and purpose Metformin is commonly prescribed to treat type 2 diabetes, and
has additional potential as a cancer prophylactic and therapeutic. Metformin activates AMPK …

The anti-cancer effects of metformin, the most widely used drug for type 2 diabetes, alone or
in combination with ionizing radiation were studied with MCF-7 human breast cancer cells …

Metformin is under evaluation as a potential anticancer agent. Expression of total and
phospho (Thr172)-adenosine monophosphate-activated kinase-α (AMPKα and pAMPKα …

Cisplatin is an extensively used chemotherapeutic drug for lung cancer, but the
development of resistance decreases its effectiveness in the treatments of non-small cell …