The pancreatic islet tissue was first described by Paul Langerhans in 18691 while he was
still a medical student. Langerhans identified a new cell type in the pancreas which had not …

322 W. Gepts pancreas was firmly established. In 1845, Bouchardat expressed the opinion,
based on autopsy findings, that diabetes was a disease of the pancreas. In 1880 …

The islets of Langerhans are small masses of specialized cells lying in the external secreting
tissue of the pancreas. In the rat, they make up about 1 per cent of the total pancreas and, if …

The title assigned me," Islet Pathology in Diabetes," implies that lesions of the islets of
Langerhans may be responsible for the diabetic state. Although this concept has merit in …

A method has been developed for the isolation of islets of Langerhans from the human
pancreas. The average number of islets isolated was 1011 islets per gram of pancreas (SD …

A comparative study of the pancreatic islets of Langerhans was undertaken in which
correlative thick-thin sectioning techniques for light and electron microscopy were used. This …

Diabetes results from the fact that not enough insulin is available to tissues. This may be
caused by an absolute deficit in insulin secretion, as when the islets are destroyed or the …

A simple method for the isolation of intact islets from the normal rat pancreas is described.
The method is based upon disruption of the acinar parenchyma by injecting Hanks solution …

The small islands of endocrine tissue dispersed throughout the substance of the pancreas
were discovered, by chance, during the middle of the last century by the medical student …

The mammalian endocrine pancreas consists of groups of hormone-secreting cells that are
dispersed throughout the exocrine tissue. These so-called endocrine islets were first …