A randomized study of solriamfetol for excessive sleepiness in narcolepsy

MJ Thorpy, C Shapiro, G Mayer, BC Corser… - Annals of …, 2019 - Wiley Online Library
Objective Solriamfetol (JZP‐110) is a selective dopamine and norepinephrine reuptake
inhibitor with wake‐promoting effects. This phase 3 study (NCT02348593) evaluated the …

Modafinil for treatment of residual excessive sleepiness in nasal continuous positive airway pressure-treated obstructive sleep apnea/hypopnea syndrome

JE Black, M Hirshkowitz - Sleep, 2005 - academic.oup.com
Abstract Study Objectives: Nasal continuous positive airway pressure (nCPAP) usually
reduces sleepiness in patients with obstructive sleep apnea/hypopnea syndrome. However …

[HTML][HTML] Efficacy of modafinil on fatigue and excessive daytime sleepiness associated with neurological disorders: a systematic review and meta-analysis

P Sheng, L Hou, X Wang, X Wang, C Huang, M Yu… - PloS one, 2013 - journals.plos.org
Background Modafinil is a novel wake-promoting agent approved by the FDA ameliorating
excessive daytime sleepiness (EDS) in three disorders: narcolepsy, shift work sleep disorder …

An overview of the clinical uses, pharmacology, and safety of modafinil

E Murillo-Rodríguez, A Barciela Veras… - ACS chemical …, 2018 - ACS Publications
Modafinil (MOD) is a wakefulness-inducing compound prescribed for treatment of excessive
daytime sleepiness as a consequence of sleep disturbances such as shift work sleep …

[HTML][HTML] Adjunct armodafinil improves wakefulness and memory in obstructive sleep apnea/hypopnea syndrome

M Hirshkowitz, JE Black, K Wesnes, G Niebler… - Respiratory …, 2007 - Elsevier
OBJECTIVE: Armodafinil is the R-enantiomer of racemic modafinil and has a significantly
longer half-life than the S-enantiomer. This study evaluated armodafinil 150mg/day as an …

Approved and investigational uses of modafinil: an evidence-based review

R Kumar - Drugs, 2008 - Springer
Modafinil is a wake-promoting agent that is pharmacologically different from other
stimulants. It has been investigated in healthy volunteers, and in individuals with clinical …

[HTML][HTML] Modafinil for excessive sleepiness associated with shift-work sleep disorder

CA Czeisler, JK Walsh, T Roth… - … England Journal of …, 2005 - Mass Medical Soc
Background Patients with shift-work sleep disorder chronically have excessive sleepiness
during night work and insomnia when attempting to sleep during the day. We evaluated the …

Armodafinil

KP Garnock-Jones, S Dhillon, LJ Scott - CNS drugs, 2009 - Springer
Abstract▴ Armodafinil is the R-enantiomer of modafinil, a wake-promoting agent, that
primarily affects areas of the brain involved in controlling wakefulness.▴ Once-daily …

Health-related quality of life effects of modafinil for treatment of narcolepsy

KM Beusterien, AE Rogers, JA Walsleben… - Sleep, 1999 - academic.oup.com
Objective: To evaluate the burden of illness of narcolepsy and assess the health-related
quality-of-life (HQL) effects of oral modafinil, a wake-promoting therapy for excessive …

Effects of modafinil on sustained attention performance and quality of life in OSA patients with residual sleepiness while being treated with nCPAP

DF Dinges, TE Weaver - Sleep medicine, 2003 - Elsevier
Background: Some patients with obstructive sleep apnea/hypopnea syndrome (OSA/HS)
who are regular users of nasal continuous positive airway pressure (nCPAP) therapy …