Conventional photodynamic therapy mainly causes a therapeutic effect on the primary tumor
through the localized generation of reactive oxygen species, while metastatic tumors remain …

Despite the clinical success of photodynamic therapy (PDT), the application of this medical
technique is intrinsically limited by the low oxygen concentrations found in cancer tumors …

Cancer therapies that generate T cell-based anti-cancer immune responses are critical for
clinical success and are favored over traditional therapies. One way to elicit T cell immune …

Photoimmunotherapy is attractive for cancer treatment due to its spatial controllability and
sustained responses. This work presents a ferrocene‐containing Ir (III) photosensitizer …

Photosensitizer-based photodynamic therapy (PDT) has been considered as a promising
modality for fighting diverse types of cancers. PDT directly inhibits local tumors by a …

Protein inactivation by reactive oxygen species (ROS) such as singlet oxygen (1O2) and
superoxide radical (O2•–) is considered to trigger cell death pathways associated with …

The immunogenicity of dying cancer cells determines the efficacy of anti-cancer therapy.
Photodynamic therapy (PDT) can induce immunogenic cell death (ICD), which is …

The past decade has witnessed major breakthroughs in cancer immunotherapy. This
development has been largely motivated by cancer cell evasion of immunological control …

The clinical application of photodynamic therapy is hindered by the high glutathione
concentration, poor cancer‐targeting properties, poor drug loading into delivery systems …

Overcoming the resistance to apoptosis and immunosuppression of tumor cells is a
significant challenge in augmenting the effect of cancer immunotherapy. Pyroptosis, a lytic …