Development of a fast and cost-effective gas chromatography–mass spectrometry method for the quantification of short-chain and medium-chain fatty acids in human …

C Lotti, J Rubert, F Fava, K Tuohy, F Mattivi… - Analytical and …, 2017 - Springer
The quantification of short-chain and medium-chain fatty acids is becoming more and more
relevant in fecal and plasma samples due to their biological impact, which has been …

Simultaneous determination of short‐chain fatty acids in human feces by HPLC with ultraviolet detection following chemical derivatization and solid‐phase extraction …

HY Wang, C Wang, LX Guo, YF Zheng… - Journal of separation …, 2019 - Wiley Online Library
Short‐chain fatty acids are currently the most studied metabolites of gut microbiota, but the
analysis of them, simultaneously, is still challenging due to their unique property and wide …

Evaluation and optimization of sample handling methods for quantification of short-chain fatty acids in human fecal samples by GC–MS

YL Hsu, CC Chen, YT Lin, WK Wu… - Journal of proteome …, 2019 - ACS Publications
The gut microbiota has attracted a great deal of interest in recent years due to its association
with many diseases. Short-chain fatty acids (SCFAs), the end products of dietary fiber …

Quantitation of circulating short-chain fatty acids in small volume blood samples from animals and humans

R Fristedt, V Ruppert, T Trower, J Cooney, R Landberg - Talanta, 2024 - Elsevier
Background The role of gut microbiota in human health has been intensively studied and
more recently shifted from emphasis on composition towards function. Function is partly …

Enhanced detection of short‐chain fatty acids using gas chromatography mass spectrometry

H Gu, P Jasbi, J Patterson, Y Jin - Current protocols, 2021 - Wiley Online Library
Short‐chain fatty acids (SCFAs) are produced mainly by intestinal microbiota and play an
important role in many host biological processes such as immune system development …

A rapid and convenient derivatization method for quantitation of short‐chain fatty acids in human feces by ultra‐performance liquid chromatography/tandem mass …

H Fu, Q Zhang, X Huang, Z Ma, X Zheng… - Rapid …, 2020 - Wiley Online Library
Rationale Short‐chain fatty acids (SCFAs) are associated with intestinal microbiota and
diseases in humans. SCFAs have a low response in mass spectrometry, and in order to …

A sensitive GC/MS detection method for analyzing microbial metabolites short chain fatty acids in fecal and serum samples

S Zhang, H Wang, MJ Zhu - Talanta, 2019 - Elsevier
Gut microbiota and their major metabolites, short-chain fatty acids (SCFAs), are recognized
as important players in gut homeostasis and metabolic disease occurance. A convenient …

Development and validation of a GC-FID method for the analysis of short chain fatty acids in rat and human faeces and in fermentation fluids

S Scortichini, MC Boarelli, S Silvi, D Fiorini - Journal of Chromatography B, 2020 - Elsevier
Short-chain fatty acids (SCFAs) are gut microbiota metabolites recognized for their beneficial
effects on the host organism. In this study, a simple and rapid sample preparation method …

Analysis of short-chain fatty acids in human feces: a scoping review

M Primec, D Mičetić-Turk, T Langerholc - Analytical biochemistry, 2017 - Elsevier
Short-chain fatty acids (SCFAs) play a crucial role in maintaining homeostasis in humans,
therefore the importance of a good and reliable SCFAs analytical detection has raised a lot …

A fast and accurate way to determine short chain fatty acids in mouse feces based on GC–MS

X Han, J Guo, Y You, M Yin, C Ren, J Zhan… - … of Chromatography B, 2018 - Elsevier
Short-chain fatty acids (SCFAs) in the gut are mainly produced by the anaerobic microbial
fermentation of unabsorbed dietary carbohydrates in the large bowel. Quantitative …