Alzheimer's disease (AD) is a progressive neurodegenerative disorder with a deadly
outcome. AD is the leading cause of senile dementia and although the pathogenesis of this …

Oxidative stress is a marker of neurodegeneration and has been recently shown to be also
involved in the early stages of the pathogenesis of various neurodegenerative disorders. In …

Alzheimer′ s disease (AD) is the most common neurodegenerative disease that causes
dementia in the elderly. Patients with AD suffer a gradual deterioration of memory and other …

One of the theories involved in the etiology of Alzheimer's disease (AD) is the oxidative
stress hypothesis. The amyloid β-peptide (Aβ), a hallmark in the pathogenesis of AD and the …

Oxidative stress occurs early in the progression of Alzheimer disease, significantly before
the development of the pathologic hallmarks, neurofibrillary tangles and senile plaques. All …

The risk of chronic diseases such as Alzheimer's disease is growing as a result of the
continuous increasing average life span of the world population, a syndrome characterized …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by loss of memory
and progressive decline of cognitive abilities. Although the pathogenesis of this disease is …

Oxidative stress is an important factor, and one that acts in the earliest stages, of Alzheimer's
disease (AD) pathogenesis. The reduction of oxidative stress has been tested as a therapy …

Various neurodegenerative disorders and syndromes are associated with oxidative stress.
The deleterious consequences of excessive oxidations and the pathophysiological role of …

Purpose: Since the description of his original patient Auguste D. with cognitive disability,
Alois Alzheimer persisted in his clinical investigations to understand this complex disease …