Sleep deprivation (SD) is a hallmark of modern society and associated with many
neuropsychiatric disorders, including depression and anxiety. However, the cellular and …

Background: Sleep deprivation (SD) plagues modern society due to the professional
demands. It prevails in patients with mood and neuroinflammatory disorders. Although …

Background Sleep deprivation (SD) leads to cognitive impairment. Neuroinflammation could
be a significant contributing factor in the same. An increase in regional brain pro …

(1) Background: Sleep deprivation (SD) triggers a range of neuroinflammatory responses.
Dexmedetomidine can improve sleep deprivation-induced anxiety by reducing …

Abstract Study Objectives: Sleep loss has pro-inflammatory effects, but the roles of specific
cell populations in mediating these effects have not been delineated. We assessed the …

Background Sleep deprivation (SD) has been suggested to have a rapid antidepressant
effect. There is substantial evidence that neuroinflammation and neuroplasticity play critical …

Hospitalized patients can develop cognitive function decline, the mechanisms of which
remain largely to be determined. Sleep disturbance often occurs in hospitalized patients …

Activated microglia-induced neuroinflammation can stimulate the hypothalamic-pituitary-
adrenal (HPA) axis to release glucocorticoids and suppress astrocyte functions, such as …

Early-life stress is a potent risk factor for development of psychiatric conditions such as
depression. The underlying mechanisms remain poorly understood. Here, we used the early …

Chronic sleep loss/fragmentation prevalent in the current 24/7 society is associated with
irreversible consequences on health and overall wellbeing. Various studies have well …