Astrocytes have many functions in the central nervous system (CNS). They support
differentiation and homeostasis of neurons and influence synaptic activity. They are …

The central nervous system (CNS) has long been recognized as a site of 'immune
privilege'because of the existence of the blood brain barrier (BBB) which presumably …

Astrocytes are abundant glial cells in the central nervous system (CNS) that control multiple
aspects of health and disease. Through their interactions with components of the blood …

Astrocytes are the most abundant cell type of the Central Nervous System (CNS) and exert
several important functions. Firstly, astrocytes strongly contribute to mechanical holding of …

In the finely balanced environment of the central nervous system astrocytes, the most
numerous cell type, play a role in regulating almost every physiological system. First found …

Astrocytes are crucial regulators of innate and adaptive immune responses in the injured
central nervous system. Depending on timing and context, astrocyte activity may exacerbate …

The neuro-immune axis has emerged as a key aspect to understand the normal function of
the Central Nervous System (CNS) as well as the pathophysiology of many brain disorders …

Although astrocytes presumably participate in maintaining the immune privilege of the
central nervous system (CNS), the mechanisms behind their immunoregulatory properties …

Multiple sclerosis is a neurologic disease caused by immune cell infiltration into the central
nervous system, resulting in gray and white matter inflammation, progressive demyelination …

It has long been thought that astrocytes, like other glial cells, simply provide a support
mechanism for neuronal function in the healthy and inflamed central nervous system (CNS) …