Animal models of drug addiction: Where do we go from here?

MC Olmstead - Quarterly Journal of Experimental …, 2006 - journals.sagepub.com
Compulsion and impulsivity are both primary features of drug addiction. Based on decades
of animal research, we have a detailed understanding of the factors (both environmental and …

Effects of chronic cocaine on impulsivity: relation to cortical serotonin mechanisms

TA Paine, HC Dringenberg, MC Olmstead - Behavioural Brain Research, 2003 - Elsevier
Drug addiction can be considered an impulse control disorder in that addicts exhibit
increased impulsivity on both behavioural and self-report measures. We investigated …

Effects of chronic administration of drugs of abuse on impulsive choice (delay discounting) in animal models

B Setlow, IA Mendez, MR Mitchell… - Behavioural …, 2009 - journals.lww.com
Drug-addicted individuals show high levels of impulsive choice, characterized by preference
for small immediate over larger but delayed rewards. Although the causal relationship …

Limbic corticostriatal systems and delayed reinforcement

RN Cardinal, CA Winstanley… - Annals of the New …, 2004 - Wiley Online Library
Impulsive choice, one aspect of impulsivity, is characterized by an abnormally high
preference for small, immediate rewards over larger delayed rewards, and can be a feature …

Recent research on impulsivity in individuals with drug use and mental health disorders: implications for alcoholism

RD Rogers, FG Moeller, AC Swann… - Alcoholism: Clinical …, 2010 - Wiley Online Library
Alcohol misuse and dependence, and many of its accompanying psychological problems,
are associated with heightened levels of impulsivity that both accelerate the development of …

Trait impulsivity predicts escalation of sucrose seeking and hypersensitivity to sucrose-associated stimuli.

L Diergaarde, T Pattij, L Nawijn… - Behavioral …, 2009 - psycnet.apa.org
Poor impulse control has been associated with compulsive drug seeking and an enhanced
risk of relapse, suggesting that impulsivity is causally related to addiction proneness and …

Time perception and impulsivity: A proposed relationship in addictive disorders

C Paasche, S Weibel, M Wittmann, L Lalanne - … & Biobehavioral Reviews, 2019 - Elsevier
Addictive disorders are characterized by impulsive behavior that leads to difficulties in
preventing certain behaviors despite negative consequences. This symptom predisposes to …

New developments in human neurocognition: clinical, genetic, and brain imaging correlates of impulsivity and compulsivity

NA Fineberg, SR Chamberlain, AE Goudriaan… - CNS …, 2014 - cambridge.org
Impulsivity and compulsivity represent useful conceptualizations that involve dissociable
cognitive functions, which are mediated by neuroanatomically and neurochemically distinct …

Impulsivity resulting from frontostriatal dysfunction in drug abuse: implications for the control of behavior by reward-related stimuli

JD Jentsch, JR Taylor - Psychopharmacology, 1999 - Springer
Drug abuse and dependence define behavioral states involving increased allocation of
behavior towards drug seeking and taking at the expense of more appropriate behavioral …

A systematic meta-review of impulsivity and compulsivity in addictive behaviors

RSC Lee, S Hoppenbrouwers, I Franken - Neuropsychology review, 2019 - Springer
It is well established that poor inhibitory control confers both a vulnerability to, and
maintenance of, addictive behaviors across the substance and behavioral spectrums. By …