Impulsivity traits and neurocognitive mechanisms conferring vulnerability to substance use disorders

A Verdejo-Garcia, N Albein-Urios - Neuropharmacology, 2021 - Elsevier
Impulsivity-the tendency to act without sufficient consideration of potential consequences in
pursuit of short-term rewards-is a vulnerability marker for substance use disorders (SUD) …

The transition to compulsion in addiction

C Lüscher, TW Robbins, BJ Everitt - Nature Reviews Neuroscience, 2020 - nature.com
Compulsion is a cardinal symptom of drug addiction (severe substance use disorder).
However, compulsion is observed in only a small proportion of individuals who repeatedly …

Anticipatory reward processing in addicted populations: a focus on the monetary incentive delay task

IM Balodis, MN Potenza - Biological psychiatry, 2015 - Elsevier
Advances in brain imaging techniques have allowed neurobiological research to temporally
analyze signals coding for the anticipation of reward. In addicted populations, both …

Prefrontal cortical–striatal dopamine receptor m RNA expression predicts distinct forms of impulsivity

NW Simon, BS Beas, KS Montgomery… - European Journal of …, 2013 - Wiley Online Library
Variation in dopamine receptor levels has been associated with different facets of
impulsivity. To further delineate the neural substrates underlying impulsive action (inability to …

Nucleus accumbens core and shell inactivation differentially affects impulsive behaviours in rats

M Feja, L Hayn, M Koch - Progress in Neuro-Psychopharmacology and …, 2014 - Elsevier
Impulsivity is a multifactorial phenomenon, determined by deficits in decision-making
(impulsive choice) and impulse control (impulsive action). Recent findings indicate that …

[HTML][HTML] Emotional and non-emotional pathways to impulsive behavior and addiction

A Torres, A Catena, A Megías, A Maldonado… - Frontiers in human …, 2013 - frontiersin.org
Impulsivity is tightly linked to addiction. However, there are several pathways by means of
which impulsive individuals are more prone to become addicts, or to suffer an addiction …

The neuropsychiatry of impulsivity

SR Chamberlain, BJ Sahakian - Current opinion in psychiatry, 2007 - journals.lww.com
Neuropsychological assessment shows great promise in the investigation of impulsivity and
its brain substrates. These results support a key role for response inhibition, a function linked …

Reinforcer pathology: implications for substance abuse intervention

WK Bickel, LN Athamneh, SE Snider, WH Craft… - Recent advances in …, 2020 - Springer
The rate at which individuals discount future rewards (ie, discounting rate) is strongly
associated with their propensity for substance abuse as well as myriad other negative health …

The utility of rat models of impulsivity in developing pharmacotherapies for impulse control disorders

CA Winstanley - British journal of pharmacology, 2011 - Wiley Online Library
High levels of impulsive behaviours are a clinically significant symptom in a range of
psychiatric disorders, such as attention deficit hyperactivity disorder, bipolar disorder …

Early environmental experience alters baseline and ethanol-induced cognitive impulsivity: relationship to forebrain 5-HT1A receptor binding

KGC Hellemans, JN Nobrega, MC Olmstead - Behavioural brain research, 2005 - Elsevier
The relationship between impulsivity and drug abuse is poorly understood despite evidence
that impulsive behaviour both predicts, and is a consequence of, drug use. Moreover …