In diarthrodial joints, the articular cartilage, calcified cartilage, and subchondral cortical and
trabecular bone form a biocomposite—referred to as the osteochondral unit—that is …

Currently, osteoarthritis (OA) is considered a disease of the entire joint, which is not simply a
process of wear and tear but rather abnormal remodelling and joint failure of an organ. The …

There is now general agreement that osteoarthritis (OA) involves all structures in the affected
joint, culminating in the degradation of the articular cartilage. It is appropriate to focus …

Osteoarthritis (OA), the most common form of degenerative joint disease, is linked to high
morbidity. It is predicted to be the single greatest cause of disability in the general population …

Osteoarthritis (OA) is the most common degenerative joint disease and a major cause of
pain and disability in adult individuals. The etiology of OA includes joint injury, obesity …

Osteoarthritis (OA) has long been considered a “wear and tear” disease leading to loss of
cartilage. OA used to be considered the sole consequence of any process leading to …

Osteochondral junction is a functional unit comprising the articular cartilage, calcified
cartilage, and subchondral bone. Alteration in any component of this composite unit can …

Objective Subchondral bone and the osteochondral junction are thought to contribute to
osteoarthritis (OA) knee pain. We undertook this study to identify osteochondral pathologies …

Osteoarthritis (OA) induces inflammation and degeneration of all joint components including
cartilage, joint capsule, bone and bone marrow, and ligaments. Particularly intraarticular …

Osteoarthritis (OA) refers to a group of mechanically-induced joint disorders to which both
genetic and acquired factors contribute. Current pathophysiological concepts focus on OA …