In recent years the demonstration that human pituitary adenomas are monoclonal in origin
provides further evidence that pituitary neoplasia arise from the replication of a single …

Lactotroph adenomas, also called prolactinomas and prolactin-secreting adenomas,
constitute nearly 80% of functioning pituitary tumors and about 30–50% of all adenomas in …

Prolactin-secreting tumors (prolactinomas) represent the most common pituitary tumor type,
accounting for 47–66% of functional pituitary tumors. Prolactinomas are usually benign and …

Pituitary lactotrophs secrete prolactin. This process is enhanced by estrogen and inhibited
by dopamine. Prolactinomas are benign neoplasms that rarely increase in size and are …

Publisher Summary Prolactinomas are classified on a clinical basis by size—
microadenomas are defined as less than 10 mm in diameter; macroadenomas are greater …

BACKGROUND/AIMS: Prolactinomas are the most common tumors of the pituitary gland.
Only few studies have documented gender-related differences in the growth and …

The molecular pathogenesis of prolactinomas has resisted elucidation; with the exception of
a RAS mutation in a single aggressive prolactinoma, no mutational changes have been …

Prolactinoma is the most frequent pituitary adenoma type, accounting for 40–66% in
epidemiological studies [1]. The estimated prevalence in various populations ranges from …

In this volume an attempt is made to provide an up to date survey of the physiology and the
pathophysiology of prolactin. Furthermore, new pharmacological developments which may …

BACKGROUND Prolactinoma is the most invasive type of pituitary adenoma and is
generally believed to be well‐differentiated adenoma and to produce only prolactin (PRL) …