MAP30 promotes apoptosis of U251 and U87 cells by suppressing the LGR5 and Wnt/β-catenin signaling pathway, and enhancing Smac expression

Y Jiang, J Miao, D Wang, J Zhou, B Liu… - Oncology …, 2018 - spandidos-publications.com
Significant antitumor activity of Momordica anti-human immunodeficiency virus protein of 30
kDa (MAP30) purified from Momordica charantia has been the subject of previous research …

MAP30 Inhibits Bladder Cancer Cell Migration and Invasion In Vitro Through Suppressing Akt Pathway and the Epithelial/Mesenchymal Transition Process

S Zhang, Z Shi, K Pang, H He, J Chen… - DNA and Cell …, 2020 - liebertpub.com
The antitumor activity of Momordica anti-human immunodeficiency virus protein of 30 kDa
(MAP30) has been proved. However, the role of MAP30 on tumor metastasis has not yet …

MAP30 inhibits autophagy through enhancing acetyltransferase p300 and induces apoptosis in acute myeloid leukemia cells

S Qian, L Sun, J Li, J Wu, G Hu, Y Han… - Oncology …, 2016 - spandidos-publications.com
Momordica anti-human immunodeficiency virus protein of 30 kDa (MAP30) has been shown
to exhibit potent antitumor activities against several solid tumors. In the present investigation …

Ribosome-inactivating protein MAP30 isolated from Momordica charantia L. induces apoptosis in hepatocellular carcinoma cells

Y Zhou, D Yang, Z Qiang, Y Meng, R Li… - Recent Patents on …, 2024 - ingentaconnect.com
Background: Ribosome-inactivating proteins (RIPs) have been reported to exert antitumor
and anti-virus activities. A recent patent CN202011568116. 7 has developed a new method …

α‑MMC and MAP30, two ribosome‑inactivating proteins extracted from Momordica charantia, induce cell cycle arrest and apoptosis in A549 human lung carcinoma …

X Fan, L He, Y Meng, G Li, L Li… - Molecular medicine …, 2015 - spandidos-publications.com
Abstract α‑Momorcharin (α‑MMC) and momordica anti‑human immunodeficiency virus
protein (MAP30), produced by Momordica charantia, are ribosome‑inactivating proteins …

The MAP30 protein from bitter gourd (Momordica charantia) seeds promotes apoptosis in liver cancer cells in vitro and in vivo

EF Fang, CZY Zhang, JH Wong, JY Shen, CH Li, TB Ng - Cancer letters, 2012 - Elsevier
Human hepatocellular carcinoma Hep G2 cells and Hep G2-bearing mice were used as in
vitro and in vivo models to assess the efficacy and safety of MAP30, a natural component …

Expression of Momordica charantia MAP30 and its antitumor effect on bladder cancer cells.

H Hlin, Z Zhi-Guo, H Cong-Hui, Z Yan… - Minerva urologica e …, 2014 - europepmc.org
Background Momordica charantia (MC) is an edible medicinal plant that is known for its
diversified biological functions. Momordica Antiviral Protein 30kD (MAP30) is a type I single …

Effects of recombinant MAP30 on cell proliferation and apoptosis of human colorectal carcinoma LoVo cells

JM Fan, J Luo, J Xu, S Zhu, Q Zhang, DF Gao… - Molecular …, 2008 - Springer
MAP30, an attractive protein isolated from bitter melon, has been previously found to have
the anti-tumor and anti-HIV activities. In this study, MAP30 was cloned and expressed and …

Effect of Momordica charantia protein on proliferation, apoptosis and the AKT signal transduction pathway in the human endometrial carcinoma Ishikawa H cell line in …

HZ Gu, RR Lin, HC Wang, XJ Zhu… - Oncology …, 2017 - spandidos-publications.com
Endometrial carcinoma (EC) is one of the most common female malignancies, and there is
an urgent requirement to explore new therapeutic strategies. In the present study, Ishikawa …

[PDF][PDF] LINC00355 inhibits apoptosis and promotes proliferation of gastric cancer cells by regulating Wnt/β-catenin signaling pathway.

PB Luan, XM Sun, J Yao - European Review for Medical & …, 2020 - europeanreview.org
OBJECTIVE: To study the expression and biological functions of long intergenic non-protein
coding ribonucleic acid 00355 (LINC00355) in gastric cancer (GC), and to explore its …