Simple Summary Childhood cancers are mostly of unknown etiology and represent
devastating diagnoses. The clinical benefits of steadily increasing tumor control and survival …

Since the 1960s, paediatric oncologists have gradually become better organised in large
study groups and participation in clinical trials is today considered as the standard of care …

Remarkable advances in the treatment of childhood and adolescent cancer have resulted in
substantial improvements in 5-and 10-year survival for the vast majority of cancer …

During the past several decades, remarkable advances have been achieved in the
treatment and survival of children with cancer. With the increasing population of childhood …

During the past three decades, multi-modality therapy for childhood cancer has resulted in
markedly improved survival. For the period of 1985 to 1997, the fiveyear survival rate for …

Purpose This report provides an overview of current childhood cancer statistics to facilitate
analysis of the impact of past research discoveries on outcome and provide essential …

With advances in therapeutic strategies for common childhood malignancies such as
leukemia, lymphoma, and central nervous system (CNS) tumors, the number of childhood …

The aim of this study was to determine therapy-related risk factors for the development of
second malignant neoplasm (SMN) after childhood cancer. The German Childhood Cancer …

Survival rates for most paediatric cancers have improved at a remarkable pace over the past
four decades. In developed countries, cure is now the probable outcome for most children …

With continuing improvements in the successful treatment of pediatric malignancies, long
term survivors of pediatric cancers and their providers are faced with new oncologic issues …