Objective Corticosteroids can attenuate the inflammatory response to cardiopulmonary
bypass, but their benefits on clinical outcomes are unclear. We conducted a meta-analysis to …

Abstract Purpose of Review Cardiopulmonary bypass for on-pump cardiac surgery induces
a systemic inflammation that may contribute to postoperative major complications. To reduce …

Corticosteroids are commonly used in the peri-operative setting for patients undergoing
cardiac surgery with cardiopulmonary bypass (CPB). The inflammatory response to CPB is …

Background Corticosteroids can effectively inhibit systemic inflammation induced by
cardiopulmonary bypass. Recently clinical trials and meta-analyses and current guidelines …

Corticosteroids are often administered prophylactically to attenuate the inflammatory
response associated with cardiac surgery using cardiopulmonary bypass (CPB). However …

Objective Steroids suppress the inflammatory response to cardiopulmonary bypass, but the
impact on death at 30 days, myocardial infarction or injury, stroke, renal failure, respiratory …

Cardiac surgery and cardiopulmonary bypass are associated with an intense activation of
the immune system. The systemic inflammatory response that develops in many cardiac …

Background Cardiopulmonary bypass (CPB) induces a systemic inflammatory reaction that
may contribute to postoperative complications. Preventing this reaction with steroids may …

From the early publications on the use of corticosteroids in infection, 1 our understanding of
their pharmacology and mode of actions has improved. Clinicians progressively have …

Traditionally, corticosteroids have been administered to patients undergoing cardiac surgery
with cardiopulmonary bypass (CPB) to ward off detrimental physiologic alterations …