[PDF][PDF] TLE4 downregulation identified by WGCNA and machine learning algorithm promotes papillary thyroid carcinoma progression via activating JAK/STAT pathway

J Lin, B Cai, Q Lin, X Lin, B Wang, X Chen - Journal of Cancer, 2024 - jcancer.org
Abstract Background: Papillary Thyroid Carcinoma (PTC), a common type of thyroid cancer,
has a pathogenesis that is not fully understood. This study utilizes a range of public …

Integrated transcriptome sequencing and weighted gene co-expression network analysis reveals key genes of papillary thyroid carcinomas

L Pan, L Zhang, J Fu, K Shen, G Zhang - Heliyon, 2024 - cell.com
Objective Papillary thyroid carcinoma (PTC) accounts for the majority of thyroid cancers and
has a high recurrence rate. We aimed to screen key genes involved in PTC to provide novel …

Identification of genes associated with Papillary Thyroid Carcinoma (PTC) for diagnosis by integrated analysis

WB Li, J Zhou, L Xu, XL Su, Q Liu… - Hormone and Metabolic …, 2016 - thieme-connect.com
Papillary thyroid carcinoma (PTC) is the most common type of thyroid carcinoma, and our
understanding of its pathogenesis is incomplete. To elucidate the mechanisms underlying …

[HTML][HTML] Identification of candidate genes associated with papillary thyroid carcinoma pathogenesis and progression by weighted gene co-expression network …

X Chen, R Wang, T Xu, Y Zhang, H Li… - Translational Cancer …, 2021 - ncbi.nlm.nih.gov
Background The genes and genetic mechanisms underlying the occurrence and
progression of papillary thyroid carcinoma (PTC) are still unknown. This study aimed to find …

Identification of potential functional genes in papillary thyroid cancer by co‑expression network analysis

ZX Ao, YC Chen, JM Lu, J Shen… - Oncology …, 2018 - spandidos-publications.com
Interactions between multiple genes are involved in the development of complex diseases.
However, there are few analyses of gene interactions associated with papillary thyroid …

Identification of key genes of papillary thyroid carcinoma by integrated bioinformatics analysis

G Xue, X Lin, JF Wu, D Pei, DM Wang… - Bioscience …, 2020 - portlandpress.com
Background: Papillary thyroid carcinoma (PTC) is one of the fastest-growing malignant
tumor types of thyroid cancer. Therefore, identifying the interaction of genes in PTC is crucial …

[HTML][HTML] Bioinformatics analysis to screen key genes in papillary thyroid carcinoma

Y Liu, S Gao, Y Jin, Y Yang, J Tai… - Oncology …, 2020 - spandidos-publications.com
Papillary thyroid carcinoma (PTC) is the most common type of thyroid carcinoma, and its
incidence has been on the increase in recent years. However, the molecular mechanism of …

Identification of potential biomarkers for papillary thyroid carcinoma by comprehensive bioinformatics analysis

M Liao, Z Wang, J Yao, H Xing, Y Hao, B Qiu - Molecular and Cellular …, 2023 - Springer
To perform bioinformatics analysis on the papillary thyroid carcinoma (PTC) gene chip
dataset to explore new biological markers for PTC. The gene expression profiles of …

Integrated bioinformatics analysis and screening of hub genes in papillary thyroid carcinoma

R Fan, L Dong, P Li, X Wang, X Chen - Plos one, 2021 - journals.plos.org
Background With the increasing incidence of papillary thyroid carcinoma (PTC), PTC
continues to garner attention worldwide; however its pathogenesis remains to be elucidated …

[HTML][HTML] Coupling of LETM1 up-regulation with oxidative phosphorylation and platelet-derived growth factor receptor signaling via YAP1 transactivation

J Lee, WK Lee, MY Seol, SG Lee, D Kim, H Kim… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Persistent cellular proliferation and metabolic reprogramming are essential processes in
carcinogenesis. Here, we performed Gene Set Enrichment Analysis (GSEA) and found that …