Toxicity of cetuximab versus cisplatin concurrent with radiotherapy in locally advanced head and neck squamous cell cancer (LAHNSCC)

L Walsh, C Gillham, M Dunne, I Fraser… - Radiotherapy and …, 2011 - Elsevier
We retrospectively reviewed acute toxicity with cetuximab and radiotherapy, comparing it
with a matched cisplatin group. The cetuximab group experienced significantly more toxicity …

Enhanced toxicity with concurrent cetuximab and radiotherapy in head and neck cancer

DI Pryor, SV Porceddu, BH Burmeister… - Radiotherapy and …, 2009 - Elsevier
PURPOSE: To report toxicity data from the first 13 consecutive patients with locally
advanced head and neck squamous cell carcinoma (LAHNSCC), ineligible for cisplatin …

[HTML][HTML] Cisplatin-based chemoradiation plus cetuximab in locally advanced head and neck cancer: a phase II clinical study

M Merlano, E Russi, M Benasso, R Corvò… - Annals of …, 2011 - Elsevier
Background Intensification of chemoradiation for advanced head and neck squamous cell
carcinoma (HNSCC) is unlikely due to toxicity. Cetuximab combined either with radiotherapy …

Efficacy of concurrent cetuximab vs. 5-fluorouracil/carboplatin or high-dose cisplatin with intensity-modulated radiation therapy (IMRT) for locally-advanced head and …

LQ Shapiro, EJ Sherman, N Riaz, J Setton, L Koutcher… - Oral oncology, 2014 - Elsevier
Objectives We previously reported inferior outcomes for locally-advanced head and neck
squamous cell carcinoma (LAHNSCC) patients treated with concurrent cetuximab vs. high …

[HTML][HTML] Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck

JA Bonner, PM Harari, J Giralt, N Azarnia… - … England Journal of …, 2006 - Mass Medical Soc
Background We conducted a multinational, randomized study to compare radiotherapy
alone with radiotherapy plus cetuximab, a monoclonal antibody against the epidermal …

Phase II study of cetuximab in combination with cisplatin and radiation in unresectable, locally advanced head and neck squamous cell carcinoma: Eastern …

AM Egloff, JW Lee, CJ Langer, H Quon, A Vaezi… - Clinical Cancer …, 2014 - AACR
Purpose: Treatment with cisplatin or cetuximab combined with radiotherapy each yield
superior survival in locally advanced squamous cell head and neck cancer (LA-SCCHN) …

Cetuximab and radiotherapy versus cisplatin and radiotherapy for locally advanced head and neck cancer: a randomized phase II trial

SM Magrini, M Buglione, R Corvò, L Pirtoli… - Journal of Clinical …, 2016 - ascopubs.org
Purpose No randomized trials have been conducted to directly compare radiotherapy (RT)
with concomitant cisplatin (CDDP) versus concomitant cetuximab (CTX) as first-line …

Cetuximab prolongs survival in patients with locoregionally advanced squamous cell carcinoma of head and neck: A phase III study of high dose radiation therapy with …

JA Bonner, PM Harari, J Giralt, N Azarnia… - Journal of Clinical …, 2004 - ascopubs.org
5507 Background: The majority of head and neck cancers overexpress the epidermal
growth factor receptor (EGFR), which is associated with aggressive tumor behavior and poor …

Cetuximab and radiation therapy versus cisplatin and radiation therapy for locally advanced head and neck cancer: Long-term survival and toxicity outcomes of a …

M Maddalo, P Borghetti, D Tomasini, R Corvò… - International Journal of …, 2020 - Elsevier
Purpose This study describes the long-term survival and toxicity outcomes of a multicenter
randomized phase 2 trial comparing radiation therapy (RT) plus cisplatin (CDDP) or …

Cisplatin, cetuximab, and radiation in locally advanced head and neck squamous cell cancer: a retrospective review

P Peddi, R Shi, B Nair, F Ampil… - Clinical Medicine …, 2015 - journals.sagepub.com
Efficacy of cisplatin versus cetuximab with radiation in locally advanced head and neck
cancer (LAHNC) was evaluated. A total of 96 patients with newly diagnosed LAHNC treated …