Supplementation of selenium reduces chemical hepatocarcinogenesis in male Sprague-Dawley rats
N Alwahaibi, J Mohamed, A Alhamadani - Journal of Trace Elements in …, 2010 - Elsevier
Selenium is an essential micronutrient mineral found mainly in soils and has been shown to
prevent certain cancers in humans and animals. However, the dose and effects of selenium …
prevent certain cancers in humans and animals. However, the dose and effects of selenium …
Effect of two selenium sources on hepatocarcinogenesis and several angiogenic cytokines in diethylnitrosamine-induced hepatocarcinoma rats
JG Liu, HJ Zhao, YJ Liu, Y Liu, XL Wang - Journal of Trace Elements in …, 2012 - Elsevier
This experiment was designed to compare the effect of two selenium sources at the dosage
of therapeutic level on hepatocarcinogenesis and angiogenic cytokines in DEN-induced …
of therapeutic level on hepatocarcinogenesis and angiogenic cytokines in DEN-induced …
Effect of dietary selenite on N-nitrosodiethylamine-induced and phenobarbital promoted multistage hepatocarcinogenesis in rat: reflection in some minerals
C Thirunavukkarasu, D Sakthisekaran - Biomedicine & pharmacotherapy, 2003 - Elsevier
Selenium (Se), a dietary micronutrient, plays a vital role in cancer chemotherapy in many
organs including the liver. We have studied the relationship between some minerals, which …
organs including the liver. We have studied the relationship between some minerals, which …
Selenium prevents tumor development in a rat model for chemical carcinogenesis
L Björkhem-Bergman, UB Torndal, S Eken… - …, 2005 - academic.oup.com
Previous studies in animals and humans have shown that selenium compounds can prevent
cancer development. In this work we studied the tumor preventive effect of selenium …
cancer development. In this work we studied the tumor preventive effect of selenium …
Effects of selenium supplementation on hepatocarcinogenesis in rats
TM Aquino, EA Porta, HM Sablan, RD Dorado - 1985 - Taylor & Francis
Four groups of weanling male Wistar rats (Groups A—D) received diethylnitrosamine (DEN,
40 ppm) in their drinking water for four weeks; after a recovery period of two weeks, they …
40 ppm) in their drinking water for four weeks; after a recovery period of two weeks, they …
The effect of selenium on cell proliferation in liver and colon
MA Tempero, EE Deschner, MS Zedeck - Biological Trace Element …, 1986 - Springer
Epidemiologic and experimental evidence support a chemoprotective role for selenium (Se)
in malignancy. Many mechanisms have been proposed to explain this phenomenon. In this …
in malignancy. Many mechanisms have been proposed to explain this phenomenon. In this …
Selenium chemoprevention of liver cancer in animals and possible human applications
SY Yu, YJ Chu, WG Li - Selenium: Present Status and Perspectives in …, 1988 - Springer
An inverse correlation between geographic distribution of liver cancer incidence and the
selenium (Se) contents of whole blood and grains was observed in Qidong county, Jiangsu …
selenium (Se) contents of whole blood and grains was observed in Qidong county, Jiangsu …
[HTML][HTML] Absence of p53 gene expression in selenium molecular prevention of chemically induced hepatocarcinogenesis in rats
NY Alwahaibi, SB Budin… - Saudi Journal of …, 2011 - journals.lww.com
Materials and Methods: Rats were divided randomly into six groups: Negative control,
positive control (diethyl nitrosamine+ 2-acetylaminofluorene), preventive group, preventive …
positive control (diethyl nitrosamine+ 2-acetylaminofluorene), preventive group, preventive …
Inhibitory effect of selenium on N-nitrosodiethylamine and phenobarbital-promoted rat liver carcinogenesis
C THIRUNAVUKKARASU… - Journal of clinical …, 2000 - jstage.jst.go.jp
The chemoprotective efficacy of selenium, a dietary micronutrient, against chemically-
induced hepatocarcinogenesis in rats was investigated. Carcinogenesis was performed by a …
induced hepatocarcinogenesis in rats was investigated. Carcinogenesis was performed by a …
The effect of sodium selenite on liver growth and thioredoxin reductase expression in regenerative and neoplastic liver cell proliferation
S Erkhembayar, A Mollbrink, LC Eriksson - Biochemical pharmacology, 2012 - Elsevier
Selenium in supra-nutritional doses is tumour-preventative in animal models and in humans.
In this work, we have compared the effect of sodium selenite on tumour growth in a rat …
In this work, we have compared the effect of sodium selenite on tumour growth in a rat …