The name netrin is derived from the Sanskrit Netr, meaning'guide'. Netrins are a family of
extracellular proteins that direct cell and axon migration during embryogenesis. Three …

Netrins are a small family of secreted proteins that are best known for their role as secreted
long-range chemotropic guidance cues. Extracellular gradients of netrin protein, established …

Netrins are a family of proteins that direct cell and axon migration during development.
Three secreted netrins (netrin-1,-3 and-4) have been identified in mammals, in addition to …

Netrins form a family of secreted and membrane‐associated proteins. Netrins are involved in
processes for axonal guidance, morphogenesis, and angiogenesis by regulating cell …

Netrins are a family of secreted proteins that direct the migration of cells and axonal growth
cones during neural development. They are bifunctional cues, attracting some cell types and …

Netrins are a family of secreted proteins that function as chemotropic axon guidance cues
during neural development. Here we demonstrate that netrin-1 continues to be expressed in …

Proper patterning of the nervous system requires that developing axons find appropriate
postsynaptic partners; this entails microns to meters of extension through an extracellular …

Recent advances highlight the versatility and complexity of this highly conserved axon and
cell migration guidance system. Characterization of netrin mutant phenotypes in worm, fly …

In 1990, the discovery of three Caenorhabditis elegans genes (unc5, unc6, unc40) involved
in pioneer axon guidance and cell migration marked a significant advancement in …

Netrins are secreted proteins that regulate axon guidance and neuronal migration. Deleted
in colorectal cancer (DCC) is a well-established netrin-1 receptor mediating attractive …