Berberine exerts anti-adipogenic activity through up-regulation of C/EBP inhibitors, CHOP and DEC2

TPT Pham, J Kwon, J Shin - Biochemical and biophysical research …, 2011 - Elsevier
Berberine exerts an anti-adipogenic activity that is associated with the down-regulation of
C/EBPα and PPARγ. Stimulation of AMP-activated kinase (AMPK) caused by inhibition of …

Berberine suppresses adipocyte differentiation via decreasing CREB transcriptional activity

J Zhang, H Tang, R Deng, N Wang, Y Zhang, Y Wang… - PLoS one, 2015 - journals.plos.org
Berberine, one of the major constituents of Chinese herb Rhizoma coptidis, has been
demonstrated to lower blood glucose, blood lipid, and body weight in patients with type 2 …

Arctiin inhibits adipogenesis in 3T3-L1 cells and decreases adiposity and body weight in mice fed a high-fat diet

B Min, H Lee, JH Song, MJ Han… - Nutrition research and …, 2014 - synapse.koreamed.org
BACKGROUND/OBJECTIVES The purpose of this study was to examine the effects and
associated mechanisms of arctiin, a lignan compound found in burdock, on adipogenesis in …

Full activation of thermogenesis in brown adipocytes requires Basigin action

K Rupar, MS Isidor, L Argemi‐Muntadas… - The FEBS …, 2023 - Wiley Online Library
Exploring mechanisms responsible for brown adipose tissue's (BAT) high metabolic activity
is crucial to exploit its energy‐dissipating ability for therapeutic purposes. Basigin (Bsg), a …

Lactate induces the development of beige adipocytes via an increase in the level of reactive oxygen species

N Esaki, T Matsui, T Tsuda - Food & Function, 2023 - pubs.rsc.org
Recent studies have indicated that lactate acts as a signaling molecule in various tissues.
We previously demonstrated that intake of an amino acid mixture combined with exercise …

[HTML][HTML] Brown adipose tissue activity as a target for the treatment of obesity/insulin resistance

AL Poher, J Altirriba, C Veyrat-Durebex… - Frontiers in …, 2015 - frontiersin.org
Presence of brown adipose tissue (BAT), characterized by the expression of the
thermogenic uncoupling protein 1 (UCP1), has recently been described in adult humans …

Dehydroabietic acid activates peroxisome proliferator‐activated receptor‐γ and stimulates insulin‐dependent glucose uptake into 3T3‐L1 adipocytes

N Takahashi, R Yao, MS Kang, M Senda, C Ando… - Biofactors, 2011 - Wiley Online Library
Dehydroabietic acid (DAA) is a food‐derived terpenoid with various bioactivities. Our
previous study has revealed that DAA activates peroxisome proliferator‐activated receptor‐γ …

Arginylation regulates adipogenesis by regulating expression of PPARγ at transcript and protein level

A Singh, AK Borah, K Deka, AP Gogoi, K Verma… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Protein modification by arginylation regulates protein stability, function and interaction. The
loss of arginylation disrupts a diverse set of fundamental cellular processes from …

[HTML][HTML] Abietic acid activates peroxisome proliferator-activated receptor-γ (PPARγ) in RAW264. 7 macrophages and 3T3-L1 adipocytes to regulate gene expression …

N Takahashi, T Kawada, T Goto, CS Kim, A Taimatsu… - FEBS letters, 2003 - Elsevier
Abietic acid is one of the terpenoids, which are multifunctional natural compounds. It has
been reported that abietic acid suppresses effects on inflammation. However, the …

Abscisic acid ameliorates atherosclerosis by suppressing macrophage and CD4+ T cell recruitment into the aortic wall

AJ Guri, SA Misyak, R Hontecillas, A Hasty… - The Journal of nutritional …, 2010 - Elsevier
Abscisic acid (ABA) is a natural phytohormone which improves insulin sensitivity and
reduces adipose tissue inflammation when supplemented into diets of obese mice. The …