Factors affecting trough plasma dabigatran concentrations in patients with atrial fibrillation and chronic kidney disease
A Skripka, D Sychev, P Bochkov, R Shevchenko… - High Blood Pressure & …, 2020 - Springer
Introduction Dabigatran is effective and widely used to prevent ischemic stroke and systemic
embolism (SE) in patients with atrial fibrillation (AF). Chronic kidney disease (CKD) also has …
embolism (SE) in patients with atrial fibrillation (AF). Chronic kidney disease (CKD) also has …
Factors influencing trough and 90-minute plasma dabigatran etexilate concentrations among patients with non-valvular atrial fibrillation
H Tomita, T Araki, T Kadokami, S Yamada… - Thrombosis …, 2016 - Elsevier
Introduction Dabigatran etexilate, a direct oral anti-coagulation agent, is used in the
prevention of thromboembolism in patients with non-valvular atrial fibrillation (NVAF) …
prevention of thromboembolism in patients with non-valvular atrial fibrillation (NVAF) …
[HTML][HTML] Factors affecting serum concentration of dabigatran in Asian patients with non-valvular atrial fibrillation
Background/purpose Dabigatran is effective in preventing ischemic stroke and systemic
embolism in patients with atrial fibrillation. Although the therapeutic window for dabigatran is …
embolism in patients with atrial fibrillation. Although the therapeutic window for dabigatran is …
Real‐world variability in dabigatran levels in patients with atrial fibrillation
Background In clinical practice, physicians are given the choice of selecting one of two
dabigatran doses based on patient characteristics, with the lower dose typically used in …
dabigatran doses based on patient characteristics, with the lower dose typically used in …
A systematic review and meta‐analysis of dabigatran peak and trough concentration in adults
JW Ng, NA Mohd Tahir, PKL Chin… - British Journal of …, 2022 - Wiley Online Library
Dabigatran etexilate is an oral direct thrombin inhibitor used in preventing thromboembolism
in patients with atrial fibrillation and several other conditions. Routine dabigatran …
in patients with atrial fibrillation and several other conditions. Routine dabigatran …
Relation between dabigatran concentration, as assessed using the direct thrombin inhibitor assay, and activated clotting time/activated partial thromboplastin time in …
K Okubo, T Kuwahara, K Takagi, M Takigawa… - The American Journal of …, 2015 - Elsevier
Dabigatran is a direct thrombin inhibitor that has been approved for preventing stroke in
patients with atrial fibrillation. In this study, we aimed to assess the associations between the …
patients with atrial fibrillation. In this study, we aimed to assess the associations between the …
Dabigatran concentration: variability and potential bleeding prediction in “real–life” patients with atrial fibrillation
P Šinigoj, RE Malmström, N Vene… - Basic & clinical …, 2015 - Wiley Online Library
Routine laboratory monitoring is currently not recommended in patients receiving dabigatran
despite its considerable variation in plasma concentration. However, in certain clinical …
despite its considerable variation in plasma concentration. However, in certain clinical …
On the monitoring of dabigatran treatment in “real life” patients with atrial fibrillation
M Skeppholm, P Hjemdahl, JP Antovic, J Muhrbeck… - Thrombosis research, 2014 - Elsevier
Introduction The oral direct thrombin inhibitor dabigatran is increasingly used to prevent
thromboembolic stroke in patients with atrial fibrillation (AF). Routine laboratory monitoring is …
thromboembolic stroke in patients with atrial fibrillation (AF). Routine laboratory monitoring is …
[HTML][HTML] Safety of low-dose dabigatran in patients with atrial fibrillation and mild renal insufficiency
H Fukaya, S Niwano, J Oikawa, R Nishinarita… - Journal of …, 2017 - Elsevier
Background Dabigatran etexilate (DE), an effective direct oral anticoagulant for patients with
atrial fibrillation (AF), should be carefully used in patients with renal insufficiency. Data on …
atrial fibrillation (AF), should be carefully used in patients with renal insufficiency. Data on …
Real-world variability in dabigatran levels in patients with atrial fibrillation: comment
J Douxfils, B Chatelain, JM Dogné… - Journal of Thrombosis and …, 2015 - jthjournal.org
We read with interest the recent prospective observational study by Chan et al.[1] The
authors aimed to investigate the interpatient and intrapatient variabilities in dabigatran …
authors aimed to investigate the interpatient and intrapatient variabilities in dabigatran …
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