Greater ethanol inhibition of presynaptic dopamine release in C57BL/6J than DBA/2J mice: role of nicotinic acetylcholine receptors

JT Yorgason, JH Rose, JM McIntosh, MJ Ferris… - Neuroscience, 2015 - Elsevier
The mesolimbic dopamine system, originating in the ventral tegmental area (VTA) and
projecting to the nucleus accumbens (NAc), has been heavily implicated in the reinforcing …

Greater ethanol-induced locomotor activation in DBA/2J versus C57BL/6J mice is not predicted by presynaptic striatal dopamine dynamics

JH Rose, ES Calipari, TA Mathews, SR Jones - PLoS One, 2013 - journals.plos.org
A large body of research has aimed to determine the neurochemical factors driving
differential sensitivity to ethanol between individuals in an attempt to find predictors of …

The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement

RA Gonzales, MO Job, WM Doyon - Pharmacology & therapeutics, 2004 - Elsevier
The neurobiological processes by which ethanol seeking and consumption are established
and maintained are thought to involve areas of the brain that mediate motivated behavior …

Moderate ethanol drinking is sufficient to alter Ventral Tegmental Area dopamine neurons activity via functional and structural remodeling of GABAergic transmission

A Ilari, L Curti, M Petrella, N Cannella, A La Rocca… - …, 2022 - Elsevier
Earlier studies have shown a major involvement of Ventral Tegmental Area (VTA) dopamine
(DA) neurons in mediating the rewarding effects of ethanol (EtOH). Much less is known on …

Acute ethanol inhibits dopamine release in the nucleus accumbens via α6 nicotinic acetylcholine receptors

ND Schilaty, DM Hedges, EY Jang, RJ Folsom… - … of Pharmacology and …, 2014 - ASPET
Electrophysiology and microdialysis studies have provided compelling evidence that
moderate to high ethanol concentrations enhance dopamine (DA) neurotransmission in the …

[引用][C] Chronic ethanol exposure alters presynaptic dopamine function in the striatum of monkeys: a preliminary study

EA Budygin, CE John, Y Mateo, JB Daunais… - Synapse, 2003 - Wiley Online Library
Current evidence suggests that dopamine (DA) neurotransmission plays a crucial role in the
positive reinforcing and stimulating actions of ethanol (Grace, 2000; Weiss and Porrino …

The peripheral dopamine 2 receptor antagonist domperidone attenuates ethanol enhancement of dopamine levels in the nucleus accumbens

JD Obray, EY Jang, AM Klomp… - Alcoholism: Clinical …, 2022 - Wiley Online Library
Background Dopamine neuron firing in the ventral tegmental area (VTA) and dopamine
release in the nucleus accumbens have been implicated in reward learning. Ethanol is …

Increased ethanol excitation of dopaminergic neurons of the ventral tegmental area after chronic ethanol treatment

MS Brodie - Alcoholism: Clinical and Experimental Research, 2002 - Wiley Online Library
Background The mesolimbic dopamine pathway, which originates in the ventral tegmental
area (VTA), is important for the rewarding effects of ethanol. Acute administration of ethanol …

GABAergic transmission modulates ethanol excitation of ventral tegmental area dopamine neurons

JW Theile, H Morikawa, RA Gonzales, RA Morrisett - Neuroscience, 2011 - Elsevier
Activation of the dopaminergic (DA) neurons of the ventral tegmental area (VTA) by ethanol
has been implicated in its rewarding and reinforcing effects. We previously demonstrated …

Chronic intermittent ethanol exposure reduces presynaptic dopamine neurotransmission in the mouse nucleus accumbens

AN Karkhanis, JH Rose, KN Huggins… - Drug and alcohol …, 2015 - Elsevier
Background Increasing evidence suggests that chronic ethanol exposure decreases
dopamine (DA) neurotransmission in the nucleus accumbens (NAc), contributing to a …