Protein O-GlcNAcylation: emerging mechanisms and functions
O-GlcNAcylation—the attachment of O-linked N-acetylglucosamine (O-GlcNAc) moieties to
cytoplasmic, nuclear and mitochondrial proteins—is a post-translational modification that …
cytoplasmic, nuclear and mitochondrial proteins—is a post-translational modification that …
Role of O-linked N-acetylglucosamine protein modification in cellular (patho)physiology
In the mid-1980s, the identification of serine and threonine residues on nuclear and
cytoplasmic proteins modified by a N-acetylglucosamine moiety (O-GlcNAc) via an O …
cytoplasmic proteins modified by a N-acetylglucosamine moiety (O-GlcNAc) via an O …
[HTML][HTML] Dynamic O-GlcNAcylation and its roles in the cellular stress response and homeostasis
JA Groves, A Lee, G Yildirir, NE Zachara - Cell Stress and Chaperones, 2013 - Elsevier
O-linked N-acetyl-β-d-glucosamine (O-GlcNAc) is a ubiquitous and dynamic post-
translational modification known to modify over 3,000 nuclear, cytoplasmic, and …
translational modification known to modify over 3,000 nuclear, cytoplasmic, and …
Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease
O-GlcNAcylation is the addition of β-DN-acetylglucosamine to serine or threonine residues
of nuclear and cytoplasmic proteins. O-linked N-acetylglucosamine (O-GlcNAc) was not …
of nuclear and cytoplasmic proteins. O-linked N-acetylglucosamine (O-GlcNAc) was not …
O-linked β-N-acetylglucosamine (O-GlcNAc): extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress
C Butkinaree, K Park, GW Hart - … et Biophysica Acta (BBA)-General Subjects, 2010 - Elsevier
BACKGROUND: Since its discovery in the early 1980s, O-linked-β-N-acetylglucosamine (O-
GlcNAc), a single sugar modification on the hydroxyl group of serine or threonine residues …
GlcNAc), a single sugar modification on the hydroxyl group of serine or threonine residues …
O-GlcNAc transferase and O-GlcNAcase: achieving target substrate specificity
AK Nagel, LE Ball - Amino acids, 2014 - Springer
O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA) catalyze the dynamic cycling of
intracellular, post-translational O-GlcNAc modification on thousands of Ser/Thr residues of …
intracellular, post-translational O-GlcNAc modification on thousands of Ser/Thr residues of …
[HTML][HTML] The O-GlcNAc Modification
NE Zachara, Y Akimoto, M Boyce, GW Hart - 2022 - europepmc.org
This chapter presents an overview of the dynamic modification of serine or threonine
hydroxyl moieties on nuclear, mitochondrial, and cytoplasmic proteins by O-linked β-N …
hydroxyl moieties on nuclear, mitochondrial, and cytoplasmic proteins by O-linked β-N …
A little sugar goes a long way: the cell biology of O-GlcNAc
MR Bond, JA Hanover - Journal of Cell Biology, 2015 - rupress.org
Unlike the complex glycans decorating the cell surface, the O-linked β-N-acetyl glucosamine
(O-GlcNAc) modification is a simple intracellular Ser/Thr-linked monosaccharide that is …
(O-GlcNAc) modification is a simple intracellular Ser/Thr-linked monosaccharide that is …
[HTML][HTML] Site-specific interplay between O-GlcNAcylation and phosphorylation in cellular regulation
Ser (Thr)-O-linked β-N-acetylglucosamine (O-GlcNAc) is a ubiquitous modification of
nucleocytoplasmic proteins. Extensive crosstalk exists between O-GlcNAcylation and …
nucleocytoplasmic proteins. Extensive crosstalk exists between O-GlcNAcylation and …
The intersections between O-GlcNAcylation and phosphorylation: implications for multiple signaling pathways
A paradigm-changing discovery in biology came about when it was found that nuclear and
cytosolic proteins could be dynamically glycosylated with a single O-linked β-N …
cytosolic proteins could be dynamically glycosylated with a single O-linked β-N …