Background The sparse connectivity of protein-protein interaction data sets makes
identification of functional modules challenging. The purpose of this study is to critically …

Protein–Protein Interaction (PPI) networks are believed to be important sources of
information related to biological processes and complex metabolic functions of the cell …

A protein-protein interaction (PPI) network is a biomolecule relationship network that plays
an important role in biological activities. Studies of functional modules in a PPI network …

Background The systematic analysis of protein-protein interactions can enable a better
understanding of cellular organization, processes and functions. Functional modules can be …

Background Clustering molecular network is a typical method in system biology, which is
effective in predicting protein complexes or functional modules. However, few studies have …

Background Biological systems can be modeled as complex network systems with many
interactions between the components. These interactions give rise to the function and …

Abstract Motivation: Protein–Protein Interaction (PPI) networks are believed to be important
sources of information related to biological processes and complex metabolic functions of …

Complex cellular processes are modular and are accomplished by the concerted action of
functional modules (Ravasz et al., Science 2002; 297: 1551–1555; Hartwell et al., Nature …

Motivation: Functional module detection within protein interaction networks is a challenging
problem due to the sparsity of data and presence of errors. Computational techniques for …

As advances in the technologies of predicting protein interactions, huge data sets portrayed
as networks have been available. Identification of functional modules from such networks is …