Cortical neurons receive balanced excitatory and inhibitory synaptic currents. Such a
balance could be established and maintained in an experience-dependent manner by …

Inhibitory neurons, although relatively few in number, exert powerful control over brain
circuits. They stabilize network activity in the face of strong feedback excitation and actively …

The rules by which neuronal activity causes long-term modification of synapses in the
central nervous system are not fully understood. Whereas competitive or correlation-based …

Plasticity in neural circuits can result from alterations in synaptic strength or connectivity, as
well as from changes in the excitability of the neurons themselves. To better understand the …

Diverse inhibitory neurons in the mammalian brain shape circuit connectivity and dynamics
through mechanisms of synaptic plasticity. Inhibitory plasticity can establish …

The broad connectivity of inhibitory interneurons and the capacity of inhibitory synapses to
be plastic make them ideal regulators of the level of excitability of many neurons …

In the adult brain, new synapses are formed and pre-existing ones are lost, but the function
of this structural plasticity has remained unclear,,,,. Learning of new skills is correlated with …

Cortical neurons receive synaptic inputs from thousands of afferents that fire action
potentials at rates ranging from less than 1 hertz to more than 200 hertz. Both the number of …

Synaptic plasticity is the experience-dependent change in connectivity between neurons
that is believed to underlie learning and memory. Here, we discuss the cellular and …

The interplay between excitation and inhibition determines the fidelity of cortical
representations. The receptive fields of excitatory neurons are often finely tuned to encoded …