Aims: To evaluate the interaction between Zuojin Pill (ZJP), a Chinese herbal formula
preparation and antidepressant agent venlafaxine in healthy volunteers. Methods: Here, the …

Abstract Venlafaxine (VEN), a first‐line antidepressant, and Zuojin Pill (ZJP), a common
herbal medicine consisting of Rhizoma Coptidis and Fructus Evodiae, are high likely co …

Venlafaxine (VEN), a first-line antidepressant, and Zuojin Pill (ZJP), a common Chinese
herbal medicine consisting of Rhizoma Coptidis and Fructus Evodiae, have a high likelihood …

Objective To investigate the effects of Chinese herb Danzhi Xiaoyao pills on the
pharmacokinetics of venlafaxine and its metabolites O-desmethylvenlafaxine (ODV) and N …

Objective: This study was conducted to investigate the effects of orally administered
apigenin on the pharmacokinetics of venlafaxine (VEN) in rats and on the metabolism of …

Objective: To study the antidepressant effect of Compound Chaigui Prescription and its
mechanism of regulating 5-hydroxytryptamine (5-HT) metabolic pathway. Methods: SD rats …

AIM: Zhi Zhu Wan (ZZW) is a classical Chinese medical formulation used for the treatment of
functional dyspepsia that attributed to Spleen-deficiency Syndrome. ZZW contains …

Objective To study the influence of CYP3A4 inhibition by ketoconazole on the disposition of
venlafaxine in individuals with different CYP2D6 pheno-and genotypes. Methods In an open …

Introduction: Quercetin and apigenin are two common dietary flavonoids widely found in
foods and fruits. Quercetin and apigenin can act as the inhibitors of CYP450 enzymes, which …

A chiral LC-MS/MS method for the simultaneous analysis of desvenlafaxine (DVS)
enantiomers in human plasma was developed and applied to a pharmacokinetic study on …