Rational use of inhaled corticosteroids for the treatment of COPD

JK Quint, A Ariel, PJ Barnes - npj Primary Care Respiratory Medicine, 2023 - nature.com
Inhaled corticosteroids (ICS) are the mainstay of treatment for asthma, but their role in
chronic obstructive pulmonary disease (COPD) is debated. Recent randomised controlled …

The dose of inhaled corticosteroids in patients with COPD: when less is better

JL Izquierdo, BG Cosio - International Journal of Chronic …, 2018 - Taylor & Francis
Background The use of inhaled corticosteroids (ICS) in combination with bronchodilators in
patients with COPD has been shown to decrease the rate of disease exacerbations and to …

Appropriate use of inhaled corticosteroids in COPD: the candidates for safe withdrawal

BP Yawn, S Suissa, A Rossi - NPJ primary care respiratory medicine, 2016 - nature.com
International guidance on chronic obstructive pulmonary disease (COPD) management
recommends the use of inhaled corticosteroids (ICS) in those patients at increased …

Efficacy and safety of inhaled corticosteroids in patients with COPD: a systematic review and meta-analysis of health outcomes

G Gartlehner, RA Hansen, SS Carson… - The Annals of Family …, 2006 - Annals Family Med
PURPOSE We wanted to review systematically the efficacy, effectiveness, and safety of
inhaled corticosteroids with respect to health outcomes in patients with chronic obstructive …

Inhaled Corticosteroids in Subjects with Chronic Obstructive Pulmonary Disease: An Old, Unfinished History

AS Melani, S Croce, G Fabbri, M Messina, E Bargagli - Biomolecules, 2024 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is one of the major causes of disability and
death. Maintenance use of inhaled bronchodilator (s) is the cornerstone of COPD …

Inhaled corticosteroids in COPD: friend or foe?

A Agusti, LM Fabbri, D Singh, J Vestbo… - European …, 2018 - Eur Respiratory Soc
The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the treatment of
patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can …

Managing the safety of inhaled corticosteroids in COPD and the risk of pneumonia

A Liapikou, M Toumbis, A Torres - Expert Opinion on Drug Safety, 2015 - Taylor & Francis
Introduction: Inhaled corticosteroids (ICS) are known to increase the risk of pneumonia in
patients with chronic obstructive pulmonary disease. To estimate the association between …

Association of inhaled corticosteroids with all-cause mortality risk in patients with COPD: a meta-analysis of 60 randomized controlled trials

H Chen, ZX Deng, J Sun, Q Huang, L Huang, YH He… - Chest, 2023 - Elsevier
Background Inhaled corticosteroids (ICSs) have been used widely in the maintenance
therapy of COPD. However, whether inhaled therapy containing ICSs can reduce the all …

Overtreatment of COPD with inhaled corticosteroids-implications for safety and costs: cross-sectional observational study

P White, H Thornton, H Pinnock, S Georgopoulou… - PloS one, 2013 - journals.plos.org
Introduction Combined inhaled long-acting beta-agonists and corticosteroids (LABA+ ICS)
are costly. They are recommended in severe or very severe chronic obstructive pulmonary …

Discontinuation of inhaled corticosteroids in COPD and the risk reduction of pneumonia

S Suissa, J Coulombe, P Ernst - Chest, 2015 - Elsevier
Background The widespread use of inhaled corticosteroids (ICSs) for COPD treatment has
been questioned. Recent studies of weaning some patients with COPD off ICSs found little …