Non-genomic regulation of vascular cell function and growth by estrogen

MR Meyer, E Haas, ER Prossnitz, M Barton - Molecular and cellular …, 2009 - Elsevier
Estrogens exert rapid, non-genomic effects, which are mediated by plasma membrane-
associated estrogen receptors (mER) mERα and mERβ, and the intracellular …

Therapeutic perspectives on the modulation of G-protein coupled estrogen receptor, GPER, function

M Rouhimoghadam, AS Lu, AK Salem… - Frontiers in …, 2020 - frontiersin.org
Estrogens exert their physiological and pathophysiological effects via cellular receptors,
named ERα, ERβ, and G-protein coupled estrogen receptor (GPER). Estrogen-regulated …

Novel non-transcriptional mechanisms for estrogen receptor signaling in the cardiovascular system: Interaction of estrogen receptor α with phosphatidylinositol 3-OH …

T Simoncini, L Fornari, P Mannella, G Varone… - Steroids, 2002 - Elsevier
Estrogen receptor (ER) signaling has been, for a long time, associated with transcriptional
processes involving nuclear translocation and binding on specific response elements …

Estrogen-related receptor α (ERRα) and ERRγ are essential coordinators of cardiac metabolism and function

T Wang, C McDonald, NB Petrenko… - … and cellular biology, 2015 - Taylor & Francis
Almost all cellular functions are powered by a continuous energy supply derived from
cellular metabolism. However, it is little understood how cellular energy production is …

Estrogens in vascular biology and disease: where do we stand today?

JF Arnal, PY Scarabin, F Trémollières… - Current Opinion in …, 2007 - journals.lww.com
Estrogens in vascular biology and disease: where do we stand... : Current Opinion in
Lipidology Estrogens in vascular biology and disease: where do we stand today? : Current …

Estrogen receptors and endocrine diseases: lessons from estrogen receptor knockout mice

SO Mueller, KS Korach - Current opinion in pharmacology, 2001 - Elsevier
The estrogen receptors ERα and ERβ are the main mediators of estrogen action and
estrogens play an important role in a variety of aspects of physiology besides their well …

Estrogen receptors and human disease

BJ Deroo, KS Korach - The Journal of clinical investigation, 2006 - Am Soc Clin Investig
Estrogens influence many physiological processes in mammals, including but not limited to
reproduction, cardiovascular health, bone integrity, cognition, and behavior. Given this …

Estrogens and the vascular endothelium

MC Cid, HW Schnaper… - Annals of the New York …, 2002 - Wiley Online Library
Estrogens exert important regulatory functions on vessel wall components, which may
contribute to the increased prevalence and severity of certain chronic inflammatory and …

Increased mortality and aggravation of heart failure in estrogen receptor-β knockout mice after myocardial infarction

T Pelzer, PAA Loza, K Hu, B Bayer, C Dienesch… - Circulation, 2005 - Am Heart Assoc
Background—Lower mortality rates among women with chronic heart failure than among
men may depend in part on the action of female sex hormones, especially estrogens. The …

Predominant role of nuclear versus membrane estrogen receptor α in arterial protection: implications for estrogen receptor α modulation in cardiovascular prevention …

E Guivarc'h, M Buscato, AL Guihot, J Favre… - Journal of the …, 2018 - Am Heart Assoc
Background Although estrogen receptor α (ER α) acts primarily as a transcription factor, it
can also elicit membrane‐initiated steroid signaling. Pharmacological tools and transgenic …