This tutorial review outlines the different template strategies that chemists have employed to
synthesise knotted molecular topologies. Metal ion coordination, hydrogen bonding and …

The first synthetic molecular trefoil knot was prepared in the late 1980s. However, it is only in
the last few years that more complex small‐molecule knot topologies have been realized …

Although many different approaches to catenanes and rotaxanes have been introduced,[1]
few strategies have been successfully developed for the synthesis of molecular knots.[2] …

Current strategies for the synthesis of molecular knots focus on twisting, folding and/or
threading molecular building blocks. Here we report that Zn (ii) or Fe (ii) ions can be used to …

Molecular composite knots have been prepared from transition metal-assembled precursors
via a Glaser acetylenic coupling reaction. The templating metal is copper (I), and the …

Knots are being discovered with increasing frequency in both biological and synthetic
macromolecules and have been fundamental topological targets for chemical synthesis for …

Over the past decades, molecular knots and links have captivated the chemical community
due to their promising mimicry properties in molecular machines and biomolecules and are …

We report on the stereoselective synthesis of trefoil knots of single topological handedness
in up to 90% yield (over two steps) through the formation of trimeric circular helicates from …

Knots are fascinating non-trivial topological entities. They are not only present in art and
history but in many scientific fields as well, from mathematics to biology. By targeting this …

The simultaneous synthesis of a molecular nine-crossing composite knot that contains three
trefoil tangles of the same handedness and a 9 7 3 link (a type of cyclic [3] catenane …