The maternal microbiome as a map to understanding the impact of prenatal stress on offspring psychiatric health

MC Kimmel, B Verosky, HJ Chen, O Davis, TL Gur - Biological psychiatry, 2023 - Elsevier
Stress and psychiatric disorders have been independently associated with disruption of the
maternal and offspring microbiome, and with increased risk of the offspring developing …

[HTML][HTML] Stress and the commensal microbiota: importance in parturition and infant neurodevelopment

TL Gur, BL Worly, MT Bailey - Frontiers in Psychiatry, 2015 - frontiersin.org
The body is colonized by an enormous array of microbes that are collectively called the
microbiota. During quiescent periods, microbial communities within the gut are relatively …

Early life stress and the development of the infant gut microbiota: implications for mental health and neurocognitive development

SC Vogel, NH Brito, BL Callaghan - Current Psychiatry Reports, 2020 - Springer
Abstract Purpose of Review We review the state of the literature examining associations
between early life stress (ELS), gut microbiota, and neurocognitive development and mental …

[HTML][HTML] Protocol for the Emory University African American maternal stress and infant gut microbiome cohort study

PA Brennan, AL Dunlop, AK Smith, M Kramer, J Mulle… - BMC pediatrics, 2019 - Springer
Background The microbial population of the human gut (the gut microbiome) is an integral
cog in the bidirectional communication axis that exists between the gastrointestinal tract and …

Treating generational stress: effect of paternal stress on development of memory and extinction in offspring is reversed by probiotic treatment

BL Callaghan, CSM Cowan… - Psychological …, 2016 - journals.sagepub.com
Early-life adversity is a potent risk factor for mental-health disorders in exposed individuals,
and effects of adversity are exhibited across generations. Such adversities are also …

Prenatal stress-induced alterations in major physiological systems correlate with gut microbiota composition in adulthood

AV Golubeva, S Crampton, L Desbonnet… - …, 2015 - Elsevier
Early-life adverse experiences, including prenatal stress (PNS), are associated with a higher
prevalence of neurodevelopmental, cardiovascular and metabolic disorders in affected …

[HTML][HTML] Neurobehavioral abnormalities following prenatal psychosocial stress are differentially modulated by maternal environment

SP Zoubovsky, MT Williams, S Hoseus… - Translational …, 2022 - nature.com
Prenatal stress (PS) is associated with increased vulnerability to affective disorders.
Transplacental glucocorticoid passage and stress-induced maternal environment alterations …

Stress gets into the belly: Early life stress and the gut microbiome

L Hantsoo, BS Zemel - Behavioural brain research, 2021 - Elsevier
Research has established that stress “gets under the skin,” impacting neuroendocrine and
neuroimmune pathways to influence risk for physical and mental health outcomes. These …

Maternal stressors and the developmental origins of neuropsychiatric risk

SG Khambadkone, ZA Cordner… - Frontiers in …, 2020 - Elsevier
The maternal environment during pregnancy is critical for fetal development and perinatal
perturbations can prime offspring disease risk. Here, we briefly review evidence linking two …

Maternal prenatal stress is associated with the infant intestinal microbiota

MAC Zijlmans, K Korpela, JM Riksen-Walraven… - …, 2015 - Elsevier
Maternal prenatal stress has been often associated with infant physical development and
health, as well as psychological functioning and behavior. However, the mechanisms …