Combined Hyperinsulinemia and Hyperglycemia, But Not Hyperinsulinemia Alone, Suppress Human Skeletal Muscle Lipolytic Activity in Vivo

V Qvisth, E Hagström-Toft, S Enoksson… - The Journal of …, 2004 - academic.oup.com
Effects of circulating insulin and glucose concentrations on skeletal muscle and adipose
tissue lipolytic activity were investigated in 10 type 1 diabetes patients with no endogenous …

No apparent suppression by insulin of in vivo skeletal muscle lipolysis in nonobese women

E Moberg, S Sjöberg… - American Journal of …, 2002 - journals.physiology.org
To investigate the antilipolytic effect of insulin in skeletal muscle and adipose tissue in vivo,
the rates of glycerol release from the two tissues were compared in 10 nonobese women …

Defective activation of skeletal muscle and adipose tissue lipolysis in type 1 diabetes mellitus during hypoglycemia

S Enoksson, SK Caprio, F Rife… - The journal of …, 2003 - academic.oup.com
The increased risk of hypoglycemia during intensified treatment of type 1 diabetes mellitus
(T1DM) patients, who have a deficient glucagon secretory response, is largely attributed to …

Lipolysis in skeletal muscle is rapidly regulated by low physiological doses of insulin

S Jacob, B Hauer, R Becker, S Artzner, P Grauer… - Diabetologia, 1999 - Springer
Aims/hypothesis. Both patients with Type II (non-insulin-dependent) diabetes mellitus and
normoglycaemic, insulin resistant subjects were shown to have an increased lipid content in …

Suppression of systemic, intramuscular, and subcutaneous adipose tissue lipolysis by insulin in humans

M Stumvoll, S Jacob, HG Wahl, B Hauer… - The Journal of …, 2000 - academic.oup.com
In addition to sc and visceral fat deposits, muscle has been shown to contain relevant
amounts of lipids whose breakdown is subject to hormonal regulation. The aim of the …

Rates of skeletal muscle and adipose tissue glycerol release in nonobese and obese subjects.

J Bolinder, DA Kerckhoffs, E Moberg… - Diabetes, 2000 - Am Diabetes Assoc
Skeletal muscle and adipose tissue lipolysis rates were quantitatively compared in 12
healthy nonobese and 14 insulin-resistant obese subjects for 3.5 h after an oral glucose …

Regulation of glucose utilization in adipose cells and muscle after long-term experimental hyperinsulinemia in rats.

LJ Wardzala, M Hirshman, E Pofcher… - The Journal of …, 1985 - Am Soc Clin Investig
The effects of chronic insulin administration on the metabolism of isolated adipose cells and
muscle were studied. Adipose cells from 2 and 6 wk insulin-treated and control rats, fed …

Suppression of whole body and regional lipolysis by insulin: effects of obesity and exercise

RC Hickner, SB Racette, EF Binder… - The Journal of …, 1999 - academic.oup.com
The aim of this study was to evaluate in premenopausal women (six endurance-trained
nonobese, six sedentary nonobese, and five sedentary obese) the suppression of whole …

Relationship between insulin-mediated glucose disposal by muscle and adipose tissue lipolysis in healthy volunteers

D Pei, YDI Chen, CB Hollenbeck… - The Journal of …, 1995 - academic.oup.com
The present study was performed in 17 nondiabetic subjects and was initiated to determine
whether enhanced adipose tissue lipolysis, either basal or catecholamine induced …

Effects of hyperglycemia on in vivo adipose tissue metabolism studied with microdialysis in IDDM subjects

TM van der Merwe, L Eklund, PAE Jansson… - Diabetes, 1994 - Am Diabetes Assoc
The effect of hyperglycemia on in vivo adipose tissue metabolism was studied with
microdialysis in seven lean patients with insulin-dependent diabetes mellitus (IDDM) …