The MLV and SV40 enhancers have a similar pattern of transcriptional activation
P Augereau, B Wasylyk - Nucleic acids research, 1984 - academic.oup.com
Activation of transcription by the Moloney Murine Leukemia Virus (MLV) and Simian Virus
(SV40) enhancers was compared by transfecting recombinants containing these enhancers …
(SV40) enhancers was compared by transfecting recombinants containing these enhancers …
Long-range activation of transcription by SV40 enhancer is affected by “inhibitory” or “permissive” DNA sequences between enhancer and promoter
E Schreiber, W Schaffner - Somatic cell and molecular genetics, 1989 - Springer
The transcriptional enhancer effect is used in many, if not all, organisms for remote control of
gene transcription. An enhancer DNA can dramatically stimulate transcription of a linked …
gene transcription. An enhancer DNA can dramatically stimulate transcription of a linked …
Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding
J Hein, S Boichuk, J Wu, Y Cheng, R Freire… - Journal of …, 2009 - Am Soc Microbiol
ABSTRACT Simian virus 40 (SV40) large T antigen (LT) is a multifunctional protein that is
important for viral replication and oncogenic transformation. Previously, infection of monkey …
important for viral replication and oncogenic transformation. Previously, infection of monkey …
Oncogenes belonging to the CSF-1 transduction pathway direct p53 tumor suppressor effects to monocytic differentiation in 32D cells
R Martinelli, G Blandino, R Scardigli, M Crescenzi… - Oncogene, 1997 - nature.com
Expression of exogenous wt-p53 in different tumor cell lines can induce growth arrest,
apoptosis, or differentiation. Several experimental works have highlighted the relevance of …
apoptosis, or differentiation. Several experimental works have highlighted the relevance of …
[HTML][HTML] CSL-p53: from senescence to CAF activation
MG Procopio, C Laszlo, GP Dotto - Cell cycle, 2016 - Taylor & Francis
Crosstalk between the epithelial and stromal compartment is essential to maintain tissue
homeostasis. Normal tissue environment can suppress the ability of incipient neoplastic …
homeostasis. Normal tissue environment can suppress the ability of incipient neoplastic …
The molecular chaperone activity of simian virus 40 large T antigen is required to disrupt Rb-E2F family complexes by an ATP-dependent mechanism
CS Sullivan, P Cantalupo, JM Pipas - Molecular and cellular …, 2000 - Taylor & Francis
The simian virus 40 large T antigen (T antigen) inactivates tumor suppressor proteins and
therefore has been used in numerous studies to probe the mechanisms that control cellular …
therefore has been used in numerous studies to probe the mechanisms that control cellular …
Simian virus 40 large T antigen's association with the CUL7 SCF complex contributes to cellular transformation
JS Kasper, H Kuwabara, T Arai, SH Ali… - Journal of …, 2005 - Am Soc Microbiol
Simian virus 40 large T antigen (T Ag) is capable of immortalizing and transforming rodent
cells. The transforming activity of T Ag is due in large part to perturbation of the tumor …
cells. The transforming activity of T Ag is due in large part to perturbation of the tumor …
How Transcription Factors Define Cell Identity and p53 Defends the Genome
T Jones - 2023 - search.proquest.com
The regulation of gene expression programs is essential for normal cellular function. These
programs are fundamentally regulated at transcription and are orchestrated by sequence …
programs are fundamentally regulated at transcription and are orchestrated by sequence …
Inhibition of SV40 large T antigen induced apoptosis by small T antigen
T Kolzau, RS Hansen, D Zahra, RR Reddel… - Oncogene, 1999 - nature.com
It is well established that the expression of simian virus 40 (SV40) early gene products
causes oncogenic transformation of rodent cells. An important aspect of this process is the …
causes oncogenic transformation of rodent cells. An important aspect of this process is the …