The aim of our meta-analysis was to review the evidence base for the efficacy and safety of
antipsychotic and antidepressant combinations in the treatment of the negative symptoms of …

BackgroundTreatment of negative symptoms in chronic schizophrenia continues to be a
major clinical issue. AimsTo analyse the efficacy of add-on antidepressants for the treatment …

Background Negative symptoms are common in people with schizophrenia and are often
difficult to treat with antipsychotic drugs. Treatment often involves the use of various add‐on …

Objective: The authors examined the safety and efficacy of antidepressants added to
antipsychotic drugs in the treatment of schizophrenia. Method: Multiple databases and …

The negative symptoms of schizophrenia comprise one of several identified symptom
clusters associated with the disorder. Although consensus on the precise components of the …

Background: Despite adequate treatment with antipsychotics, a substantial number of
patients with schizophrenia demonstrate only suboptimal clinical outcome. To overcome this …

Background. Depression is common in people with schizophrenia and is associated with
substantial morbidity and an increased risk of suicide. Our aim was to review systematically …

Objective To evaluate the efficacy and safety of antidepressant augmentation of
antipsychotics in schizophrenia. Methods Systematic literature search (PubMed/MEDLINE …

We focused on the application of antidepressants in schizophrenia treatment in this review.
Augmentation of antidepressants with antipsychotics is a common clinical practice to treat …

Background Antipsychotics improve the positive symptoms of schizophrenia. However, little
is known about the extent of antidepressive effects of antipsychotics and their correlation …