[HTML][HTML] Recent technological updates and clinical applications of induced pluripotent stem cells

S Diecke, SM Jung, J Lee, JH Ju - The Korean journal of internal …, 2014 - ncbi.nlm.nih.gov
Induced pluripotent stem cells (iPSCs) were first described in 2006 and have since emerged
as a promising cell source for clinical applications. The rapid progression in iPSC …

Autologous induced pluripotent stem cell–based cell therapies: Promise, progress, and challenges

M Madrid, C Sumen, S Aivio, N Saklayen - Current protocols, 2021 - Wiley Online Library
The promise of human induced pluripotent stem cells (iPSCs) lies in their ability to serve as
a starting material for autologous, or patient‐specific, stem cell–based therapies. Since the …

Induced pluripotent stem cell (iPSCs) and their application in immunotherapy

Z Jiang, Y Han, X Cao - Cellular & molecular immunology, 2014 - nature.com
The ever-improving technology to generate induced pluripotent stem cells (iPSCs) has
increased their potential use as novel candidates for disease modeling, drug screening …

[HTML][HTML] Methods of induced pluripotent stem cells for clinical application

T Seki, K Fukuda - World journal of stem cells, 2015 - ncbi.nlm.nih.gov
Reprograming somatic cells using exogenetic gene expression represents a
groundbreaking step in regenerative medicine. Induced pluripotent stem cells (iPSCs) are …

Induced pluripotent stem cells (iPSCs)—roles in regenerative therapies, disease modelling and drug screening

MAM Aboul-Soud, AJ Alzahrani, A Mahmoud - Cells, 2021 - mdpi.com
The discovery of induced pluripotent stem cells (iPSCs) has made an invaluable contribution
to the field of regenerative medicine, paving way for identifying the true potential of human …

Induced Pluripotent Stem Cells: Progress toward Clinical Translation from Bench to Bedside

AOJ Fakoya, AE Omole, N Satyadev… - Handbook of stem cell …, 2022 - Springer
Induced pluripotent stem cells (iPSCs) offer huge promise and potential in the creation of
patient-specific stem cells for modeling human diseases, drug development and testing, and …

[HTML][HTML] Induced pluripotent stem cells and personalized medicine: current progress and future perspectives

YS Chun, K Byun, B Lee - Anatomy & cell biology, 2011 - ncbi.nlm.nih.gov
Generation of induced pluripotent stem cells (iPSCs) has revolutionized the field of
regenerative medicine by providing researchers with a unique tool to derive disease-specific …

[PDF][PDF] Patient-specific induced pluripotent stem cells as a platform for disease modeling

W Young, SL D'Souza, IR Lemischka… - Drug Discovery and …, 2012 - researchgate.net
The breakthrough development of induced pluripotent stem cell (iPSC) technology is not
only revolutionizing basic stem cell science but is also spurring efforts to reprogram one …

iPS cells: a game changer for future medicine

H Inoue, N Nagata, H Kurokawa, S Yamanaka - The EMBO journal, 2014 - embopress.org
The induced pluripotent stem cell (i PSC) technology is instrumental in advancing the fields
of disease modeling and cell transplantation. We herein discuss the various issues …

Roadblocks in the Path of iPSC to the Clinic

E Garreta, S Sanchez, J Lajara, N Montserrat… - Current transplantation …, 2018 - Springer
Abstract Purpose of Review The goal of this paper is to highlight the major challenges in the
translation of human pluripotent stem cells into a clinical setting. Recent Findings Innate …