Exposure to different surface-modified polystyrene nanoparticles caused anxiety, depression, and social deficit in mice via damaging mitochondria in neurons
Y Ma, D Xu, Z Wan, Z Wei, Z Chen, Y Wang… - Science of The Total …, 2024 - Elsevier
Nanoplastics (NPs) are unavoidable hazardous materials that result from the human
production and use of plastics. While there is evidence that NPs can bioaccumulate in the …
production and use of plastics. While there is evidence that NPs can bioaccumulate in the …
Brain single-nucleus transcriptomics highlights that polystyrene nanoplastics potentially induce Parkinson's disease-like neurodegeneration by causing energy …
B Liang, Y Huang, Y Zhong, Z Li, R Ye, B Wang… - Journal of Hazardous …, 2022 - Elsevier
With the prevalence of nanoplastics in daily life, human exposure is inevitable. However,
whether and how nanoplastics cause neurotoxicity in humans remains obscure. Herein, we …
whether and how nanoplastics cause neurotoxicity in humans remains obscure. Herein, we …
Polystyrene nanoplastics penetrate across the blood-brain barrier and induce activation of microglia in the brain of mice
S Shan, Y Zhang, H Zhao, T Zeng, X Zhao - Chemosphere, 2022 - Elsevier
Microplastics (MPs) have been well demonstrated as potential threats to the ecosystem,
whereas the neurotoxicity of MPs in mammals remains to be elucidated. The current study …
whereas the neurotoxicity of MPs in mammals remains to be elucidated. The current study …
Nano polystyrene induced changes in anxiety and learning behaviour are mediated through oxidative stress and gene disturbance in mouse brain regions
A Sharma, M Kaur, K Sharma, S kumar Bunkar, P John… - Neurotoxicology, 2023 - Elsevier
It is widely reported now that nanoplastic particles have potential neurotoxic effects and may
disturb central nervous system (CNS) function. However, the mechanism behind these toxic …
disturb central nervous system (CNS) function. However, the mechanism behind these toxic …
Exposure to polystyrene nanoplastics induces an anxiolytic-like effect, changes in antipredator defensive response, and DNA damage in Swiss mice
ATB Guimarães, ÍN Freitas, NM Mubarak… - Journal of hazardous …, 2023 - Elsevier
Although the in vivo toxicity of nanoplastics (NPs) has already been reported in different
model systems, their effects on mammalian behavior are poorly understood. Thus, we aimed …
model systems, their effects on mammalian behavior are poorly understood. Thus, we aimed …
Dysregulation of the microbiota-brain axis during long-term exposure to polystyrene nanoplastics in rats and the protective role of dihydrocaffeic acid
W Jiang, C Hu, Y Chen, Y Li, X Sun, H Wu… - Science of The Total …, 2023 - Elsevier
Polystyrene nano-plastics (PS-NPs) can be accumulated in the food chain and can
penetrate biological barriers to affect multiple physiological functions. However, the adverse …
penetrate biological barriers to affect multiple physiological functions. However, the adverse …
[HTML][HTML] Polystyrene micro-and nanoparticles exposure induced anxiety-like behaviors, gut microbiota dysbiosis and metabolism disorder in adult mice
X Chen, L Xu, Q Chen, S Su, J Zhuang… - … and Environmental Safety, 2023 - Elsevier
Plastics have been proven to be a potential threat to the ecosystem, and their toxicity
mechanism is still uncertain. In the ecological environment, plastics can be degraded into …
mechanism is still uncertain. In the ecological environment, plastics can be degraded into …
Neonatal Exposure to Polystyrene Nanoplastics Impairs Microglia-Mediated Synaptic Pruning and Causes Social Behavioral Defects in Adulthood
L Zou, X Xu, Y Wang, FF Lin, C Zhang… - Environmental …, 2024 - ACS Publications
The increasing prevalence and persistence of nanoplastics (NPs) have become critical
environmental concerns. These particles have the potential to enter the food chain and …
environmental concerns. These particles have the potential to enter the food chain and …
Cerebral neurotoxicity of amino-modified polystyrene nanoplastics in mice and the protective effects of functional food Camellia pollen
H Bai, Y Wu, H Li, Y Zhu, R Che, F Wang… - Science of The Total …, 2024 - Elsevier
Accumulating evidence suggests that nanoplastics contribute to an increased risk of brain
damage, however, the precise underlying mechanisms remain unclear. Here, we subjected …
damage, however, the precise underlying mechanisms remain unclear. Here, we subjected …
Recent progress and future directions of the research on nanoplastic-induced neurotoxicity
SW Han, J Choi, KY Ryu - Neural regeneration research, 2024 - journals.lww.com
Many types of plastic products, including polystyrene, have long been used in commercial
and industrial applications. Microplastics and nanoplastics, plastic particles derived from …
and industrial applications. Microplastics and nanoplastics, plastic particles derived from …
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