[HTML][HTML] Calcium-activated potassium current: a novel ion channel candidate in atrial fibrillation
S Nattel - The Journal of physiology, 2009 - ncbi.nlm.nih.gov
Atrial fibrillation (AF) is the most common clinical arrhythmia, and an important contributor to
cardiovascular morbidity and mortality (Kannel & Benjamin, 2008). Currently available …
cardiovascular morbidity and mortality (Kannel & Benjamin, 2008). Currently available …
Cardiac ion channels and mechanisms for protection against atrial fibrillation
M Grunnet, BH Bentzen, US Sørensen… - Reviews of Physiology …, 2012 - Springer
Atrial fibrillation (AF) is recognised as the most common sustained cardiac arrhythmia in
clinical practice. Ongoing drug development is aiming at obtaining atrial specific effects in …
clinical practice. Ongoing drug development is aiming at obtaining atrial specific effects in …
Ionic Determinants of Atrial Fibrillation and Ca2+ Channel Abnormalities: Cause, Consequence, or Innocent Bystander?
S Nattel - Circulation research, 1999 - Am Heart Assoc
Over the past several years, there has been increasing interest in understanding the basic
mechanisms underlying atrial fibrillation (AF). The rise in interest is partly related to the …
mechanisms underlying atrial fibrillation (AF). The rise in interest is partly related to the …
Role of small-conductance calcium-activated potassium channels in atrial electrophysiology and fibrillation in the dog
XY Qi, JG Diness, BJJM Brundel, XB Zhou, P Naud… - Circulation, 2014 - Am Heart Assoc
Background—Recent evidence points to functional Ca2+-dependent K+ (SK) channels in
the heart that may govern atrial fibrillation (AF) risk, but the underlying mechanisms are …
the heart that may govern atrial fibrillation (AF) risk, but the underlying mechanisms are …
Calcium handling and atrial fibrillation
Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia in the clinical
setting. It is associated with substantial cardiovascular morbidity and mortality. Recent …
setting. It is associated with substantial cardiovascular morbidity and mortality. Recent …
Calcium dysregulation in atrial fibrillation: the role of CaMKII
Atrial fibrillation (AF) is the most frequently encountered clinical arrhythmia and is associated
with increased morbidity and mortality. Ectopic activity and reentry are considered major …
with increased morbidity and mortality. Ectopic activity and reentry are considered major …
The multidimensional role of calcium in atrial fibrillation pathophysiology: mechanistic insights and therapeutic opportunities
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, and its prevalence is
increasing with the ageing of the population. Presently available treatment options are far …
increasing with the ageing of the population. Presently available treatment options are far …
Enhanced Ca2+-Dependent SK-Channel Gating and Membrane Trafficking in Human Atrial Fibrillation
Background: Small-conductance Ca2+-activated K+ (SK)–channel inhibitors have
antiarrhythmic effects in animal models of atrial fibrillation (AF), presenting a potential novel …
antiarrhythmic effects in animal models of atrial fibrillation (AF), presenting a potential novel …
[HTML][HTML] Role of calcium-activated potassium channels in atrial fibrillation pathophysiology and therapy
JG Diness, BH Bentzen, US Sørensen… - Journal of …, 2015 - journals.lww.com
Small-conductance Ca 2+-activated potassium (SK) channels are relative newcomers within
the field of cardiac electrophysiology. In recent years, an increased focus has been given to …
the field of cardiac electrophysiology. In recent years, an increased focus has been given to …
Effect of antiarrhythmic drugs on small conductance calcium–activated potassium channels
R Simó-Vicens, DRP Sauter, M Grunnet… - European Journal of …, 2017 - Elsevier
Atrial fibrillation (AF) is the most common type of arrhythmia. Current pharmacological
treatment for AF is moderately effective and/or increases the risk of serious ventricular …
treatment for AF is moderately effective and/or increases the risk of serious ventricular …