[HTML][HTML] Recent advances on quinazoline derivatives: A potential bioactive scaffold in medicinal chemistry

R Karan, P Agarwal, M Sinha, N Mahato - ChemEngineering, 2021 - mdpi.com
This paper intended to explore and discover recent therapeutic agents in the area of
medicinal chemistry for the treatment of various diseases. Heterocyclic compounds …

Current perspectives on quinazolines with potent biological activities: A review

T Gupta, A Rohilla, A Pathak, MJ Akhtar… - Synthetic …, 2018 - Taylor & Francis
Quinazoline is a heterocyclic compound having biological activities. It is aromatic in nature
having bicyclic structure containing benzene ring and pyrimidine ring. Quinazoline and its …

Chemical characteristics, synthetic methods, and biological potential of quinazoline and quinazolinone derivatives

M Asif - International journal of medicinal chemistry, 2014 - Wiley Online Library
The heterocyclic fused rings quinazoline and quinazolinone have drawn a huge
consideration owing to their expanded applications in the field of pharmaceutical chemistry …

An overview of quinazolines: Pharmacological significance and recent developments

V Alagarsamy, K Chitra, G Saravanan… - European journal of …, 2018 - Elsevier
Most of the drugs and pharmacologically relevant molecules possess heterocyclic ring
structures and presence of hetero atoms or groupings divulges privileged specificities in …

[PDF][PDF] Quinazoline marketed drugs

TP Selvam, PV Kumar - Research in Pharmacy, 2015 - researchgate.net
Quinazoline is the main six-membered heterocyclic ring system reported for their biological
activities, compounds with multiple pharmacophores, which bring together knowledge of a …

[HTML][HTML] Medicinal chemistry of quinazolines as analgesic and anti-inflammatory agents

MF Zayed - ChemEngineering, 2022 - mdpi.com
Quinazoline is an essential scaffold, known to be linked with various biological activities.
Some of the prominent biological activities of this system are analgesic, anti-inflammatory …

[HTML][HTML] Chemical insights into the synthetic chemistry of quinazolines: Recent advances

M Faisal, A Saeed - Frontiers in chemistry, 2021 - frontiersin.org
In medicinal chemistry, one of the most significant heterocyclic compounds are quinazolines,
possessing broad range of biological properties such as anti-bacterial, anti-fungal, anti-HIV …

[HTML][HTML] Quinazolinone and quinazoline derivatives: recent structures with potent antimicrobial and cytotoxic activities

E Jafari, MR Khajouei, F Hassanzadeh… - Research in …, 2016 - journals.lww.com
The heterocyclic compounds have a great importance in medicinal chemistry. One of the
most important heterocycles in medicinal chemistry are quinazolines possessing wide …

Synthetic approaches, functionalization and therapeutic potential of quinazoline and quinazolinone skeletons: The advances continue

I Khan, A Ibrar, W Ahmed, A Saeed - European journal of medicinal …, 2015 - Elsevier
The presence of N-heterocycles as an essential structural motif in a variety of biologically
active substances has stimulated the development of new strategies and technologies for …

[HTML][HTML] Medicinal chemistry of quinazolines as anticancer agents targeting tyrosine kinases

MF Zayed - Scientia Pharmaceutica, 2023 - mdpi.com
Cancer is a large group of diseases that can affect any organ or body tissue due to the
abnormal cellular growth with the unknown reasons. Many of the existing chemotherapeutic …