Unraveling plant natural chemical diversity for drug discovery purposes
E Lautié, O Russo, P Ducrot, JA Boutin - Frontiers in pharmacology, 2020 - frontiersin.org
The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …
benefit from the immense natural chemical diversity is a concern in many laboratories …
[HTML][HTML] Discovery and resupply of pharmacologically active plant-derived natural products: A review
AG Atanasov, B Waltenberger… - Biotechnology …, 2015 - Elsevier
Medicinal plants have historically proven their value as a source of molecules with
therapeutic potential, and nowadays still represent an important pool for the identification of …
therapeutic potential, and nowadays still represent an important pool for the identification of …
Natural products in drug discovery–creating a new vision
GA Cordell - Phytochemistry Reviews, 2002 - Springer
Abstract “If only they had chosen to develop natural product drugs in a sustainable manner
at the turn of the century”. In 2050, when the Earth has a population of at least 9 billion, will …
at the turn of the century”. In 2050, when the Earth has a population of at least 9 billion, will …
Plant-derived natural products for drug discovery: current approaches and prospects
N Nasim, IS Sandeep, S Mohanty - The Nucleus, 2022 - Springer
Nature has abundant source of drugs that need to be identified/purified for use as essential
biologics, either individually or in combination in the modern medical field. These drugs are …
biologics, either individually or in combination in the modern medical field. These drugs are …
The evolving role of natural products in drug discovery
FE Koehn, GT Carter - Nature reviews Drug discovery, 2005 - nature.com
Natural products and their derivatives have historically been invaluable as a source of
therapeutic agents. However, in the past decade, research into natural products in the …
therapeutic agents. However, in the past decade, research into natural products in the …
Strategies to diversify natural products for drug discovery
G Li, HX Lou - Medicinal research reviews, 2018 - Wiley Online Library
Natural product libraries contain specialized metabolites derived from plants, animals, and
microorganisms that play a pivotal role in drug discovery due to their immense structural …
microorganisms that play a pivotal role in drug discovery due to their immense structural …
Natural products in drug discovery: present status and perspectives
G Molinari - Pharmaceutical Biotechnology, 2009 - Springer
Natural products and their derivatives have been and continue to be rich sources for drug
discovery. However, natural products are not drugs. They are produce in nature and through …
discovery. However, natural products are not drugs. They are produce in nature and through …
Medicines from nature: are natural products still relevant to drug discovery?
AL Harvey - Trends in Pharmacological Sciences, 1999 - cell.com
Historically, most drugs have been derived from natural products, but there has been a shift
away from their use with the increasing predominance of molecular approaches to drug …
away from their use with the increasing predominance of molecular approaches to drug …
Natural products as a foundation for drug discovery
JA Beutler - Current protocols in pharmacology, 2019 - Wiley Online Library
Many natural products have been used as drugs for the treatment of diverse indications.
Although most US pharmaceutical companies have reduced or eliminated their in‐house …
Although most US pharmaceutical companies have reduced or eliminated their in‐house …
Plant-derived natural products: a source for drug discovery and development
N Chaachouay, L Zidane - Drugs and Drug Candidates, 2024 - mdpi.com
For thousands of years, nature has been a source of medical substances, and an
astounding numeral of contemporary remedies have been identified from natural origins …
astounding numeral of contemporary remedies have been identified from natural origins …