BACKGROUND: Although decennial adult boosters of tetanus and diphtheria toxoids are
recommended in Canada and the United States, a second dose of pertussis vaccine during …

Background Recombinant pertussis vaccines inducing long-lasting immune responses
could help to control the rise in pertussis. We here report on persisting antibody responses 2 …

As vaccine-induced immunity and protection following natural pertussis infection wane over
time, adults and adolescents may develop pertussis and become transmitters to unprotected …

Background. Booster vaccination against tetanus and diphtheria at 10-year intervals is
commonly recommended. Reduced antigen content diphtheria and tetanus toxoids and …

In a clinical trial, adolescents who had received a booster dose of reduced dose diphtheria–
tetanus-5-component acellular pertussis vaccine (Adacel®, Tdap) 5 years earlier maintained …

Reduced-antigen-content diphtheria–tetanus–acellular-pertussis (dTpa) vaccines are
predominantly recommended for once-in-a-lifetime use. A second dTpa (Boostrix™ …

Background. The recent introduction of acellular pertussis vaccines (Pa) offers the possibility
of booster doses in older children and adults. This can be conveniently accomplished by …

Boostrix® is a three-pertussis component, combined, reduced-antigen content tetanus,
diphtheria, and acellular pertussis (Tdap) booster vaccine administered as a single …

Background The immunogenicity of acellular pertussis vaccines and persistence of immunity
after vaccination might be improved by using genetically inactivated pertussis toxin (PTgen) …

Abstract▴ The reduced-antigen combined diphtheria-tetanus-acellular pertussis vaccine
(dTpa) is intended for use as a booster dose in individuals aged≥ 4 years.▴ A single dose …