Importance In most countries, the diphtheria-tetanus–acellular pertussis (DTaP) vaccine is
administered as a 3-dose infant series followed by additional booster doses in the first 5 …

Background. Unexpected waning of immunity after pertussis vaccination is now well
described. In this study we examined whether prior vaccination with whole-cell pertussis …

We compared immunogenicity and reactogenicity of a single dose of DTaP vaccine
(containing tetanus and diphtheria toxoids and four acellular pertussis antigens) with …

Abstract In 2005, the Advisory Committee on Immunization Practices (ACIP) recommended
that the newly licensed tetanus, diphtheria, and acellular pertussis (Tdap) vaccine replace a …

Pertussis is one of the only vaccine-preventable diseases with increasing incidence in the
United States. The incidence of pertussis infection in adolescents is a growing concern; it …

Pertussis is a vaccine preventable respiratory infection. Young infants are at high risk of
developing severe complications from infection. Despite high rates of pediatric vaccine …

A trial to compare the reactogenicity and immunogenicity of a reduced antigen content
diphtheria–tetanus–acellular pertussis (dTpa) vaccine with diphtheria–tetanus–whole-cell …

Currently, there are 2 tetanus and reduced antigen content diphtheria and acellular
pertussis vaccines (Tdap vaccines; called dTpa in Europe) available for the immunization of …

BACKGROUND: Older adults, especially those over 65 years, are at risk of more severe
morbidity from diphtheria, tetanus and pertussis and may transmit pertussis to unvaccinated …

BACKGROUND AND OBJECTIVES: Pertussis incidence is increasing, possibly due to the
introduction of acellular vaccines, which may have decreased the durability of immune …