Purpose Despite high national vaccination coverage with tetanus toxoid, reduced diphtheria
toxoid, and acellular pertussis (Tdap) vaccines among US adolescents, rates of adolescent …

Background. Pertussis is among the most poorly controlled bacterial vaccine-preventable
diseases in the United States. In 2006, a tetanus, reduced-dose diphtheria, and acellular …

German adolescents (n= 123) without previous pertussis vaccination, no history of pertussis
and low IgG-anti-pertussis-toxin (PT) levels received one dose of the Tdap vaccine …

Background: Adult formulation tetanus and diphtheria toxoids and acellular pertussis
vaccines (Tdap) have been developed to prevent pertussis in adolescents and adults. There …

Background Acellular pertussis vaccines were initially licensed based on placebo-controlled
efficacy trials, but such trials are no longer ethical. The effectiveness of current pertussis …

Background. The incidence of pertussis in the United States has been increasing. Adult
vaccination is important to reduce disease burden and prevent transmission to infants at …

Abstract Background Pertussis persists in Manitoba despite the universal availability of
pertussis vaccines. Recent cases have included previously vaccinated individuals, raising …

A sixth dose of tetanus, diphtheria, acellular pertussis (Tdap) vaccine in adolescents might
produce a differing reactogenicity and/or immunogenicity response depending on the …

The reduced antigen content diphtheria, tetanus and pertussis (dTpa) vaccine (Boostrix™)
has been shown to induce a strong booster response to all the vaccine components in 4–6 …

A large, randomized, placebo-controlled clinical trial in Italy on two three-component
pertussis vaccines, given as DTaP in infancy, one manufactured by SmithKline and …