Inheritance of familial hypercholesterolaemia undoubtedly increases the likelihood that
lipoprotein (a) will be raised. However, in familial hypercholesterolaemia when ASCVD …

Abstract Purpose of Review Individuals with familial hypercholesterolemia have very high
risk of cardiovascular disease due to lifelong elevations in LDL cholesterol. Elevated …

Background The reason why lipoprotein (a) concentrations are raised in individuals with
clinical familial hypercholesterolaemia is unclear. We tested the hypotheses that high …

In lipid composition lipoprotein (a), or Lp (a), resembles low-density lipoprotein (LDL), but Lp
(a) is denser and larger.'" 2 Its unique immunologic characteristics are due to apolipoprotein …

Abstract Purpose of Review Familial hypercholesterolemia is a high cardiovascular risk
disorder. We will review the role of lipoprotein (a) in cardiovascular risk and in aortic valve …

Background: The role of lipoprotein (a)[Lp (a)] as a predictor of cardiovascular disease
(CVD) in patients with heterozygous familial hypercholesterolemia (HFH) is unclear. We …

Lipoprotein (a)[Lp (a)] is a quantitative genetic trait that in the general population is largely
controlled by 1 major locus—the locus for the apolipoprotein (a)[apo (a)] gene. Sibpair …

Familial hypercholesterolaemia (FH) is a clinical syndrome that results from mutations in the
low-density lipoprotein receptor (LDLR) gene. The worldwide prevalence of homozygosity is …

Familial hypercholesterolemia carries a marked increase in the risk of coronary heart
disease (CHD), but there is considerable variation between individuals in susceptibility to …

Over the last 10 years, there have been advances on several aspects of lipoprotein (a)
which are reviewed in the present article. Since the standard immunoassays for measuring …