Metastatic melanoma still remains one the most difficult cancers to overcome. The aim of our
research was the design of anti-tumour triazene compounds 3 for application to a melanoma …

Breast cancer is the first cause of cancer death in women. Many patients are resistant to
current therapies, and even those were sensitive at first may eventually become resistant …

A series of novel thiosemicarbazone analogs (4a–t, 6a–j) were synthesized and evaluated
for their cytotoxic activities. The obtained results showed that thiochromanone-based …

Abstract Background/Aim Breast cancer is one of the world's leading cause of deaths in
women. This study evaluated the in-vitro anticancer activity of different thiosemicarbazones …

The use of molecules inspired by natural scaffolds has proven to be a very promising and
efficient method of drug discovery. In this work, capsaicin, a natural product from Capsicum …

Malignant melanoma is the most dangerous type of skin cancer. Although recent progress in
treatment has been achieved, lack of response, drug resistance and relapse remain major …

The C-2 arylidene analog (compound 3) of pentacyclic triterpenoid Lantadene A (compound
1) was synthesized and evaluated by the National Cancer Institute, USA, for in vitro …

As part of a research programme aimed at the synthesis of compounds with antiviral,
antibacterial and antitumor properties and their spectroscopic characterization, new …

The paper describes synthesis of several novel thiosemicarbazone derivatives. Furthermore,
crystal and molecular structure of 4-diethylamino-salicylaldehyde 4 …

Abstract (Z)-N'-(5-methoxy-2-oxoindolin-3-ylidene) thiomorpholine-4-carbothiohydrazide
(MeOIstTmor),(Z)-N'-(5-methoxy-2-oxoindolin-3-ylidene)-2, 6-dimethylmorpholine-4 …