Background and Purpose Predicting the risk of drug‐induced adverse psychiatric effects is
important but currently not possible in non‐human species. We investigated whether the …

Rationale Affective biases are hypothesised to contribute to the cause and treatment of
mood disorders. We have previously found that affective biases, associated with learning …

Rationale Affective biases seemingly play a crucial role for the onset and development of
depression. Acute treatment with monoamine-based antidepressants positively influences …

The subjective measures used to study mood disorders in humans cannot be replicated in
animals; however, the increasing application of objective neuropsychological methods …

Rationale Affective states are known to influence behaviour in humans resulting in cognitive
affective biases, which may play an important role in the development and treatment of …

Major depressive disorder (MDD) affects more than 10% of the population, although our
understanding of the underlying aetiology of the disease and how antidepressant drugs act …

Depression is one of the most common but poorly understood psychiatric conditions.
Although drug treatments and psychological therapies are effective in some patients, many …

Rationale There is an urgent need to identify behaviours in animals that can provide insight
into the aetiology and potential treatment of depression in humans. Objectives This study …

Validated measures of animal affect are crucial to research spanning numerous disciplines.
Judgement bias, which assesses decision-making under ambiguity, is a promising measure …

Studies in human and non‐human species suggest that decision‐making behaviour can be
biased by an affective state, also termed an affective bias. To study these behaviours in non …