Autophagy is an evolutionarily conserved lysosomal degradation pathway that eliminates
cytosolic proteins, macromolecules, organelles, and protein aggregates. Activation of …

Basal autophagy plays a critical role in maintaining cellular homeostasis and genomic
integrity by degrading aged or malfunctioning organelles and damaged or misfolded …

Autophagy is a catabolic process that captures cellular waste and degrades them in the
lysosome. The main functions of autophagy are quality control of cytosolic proteins and …

Autophagy is intricately linked with many intracellular signaling pathways, particularly
nutrient-sensing mechanisms and cell death signaling cascades. In cancer, the roles of …

The functional relevance of autophagy in tumor formation and progression remains
controversial. Autophagy can promote tumor suppression during cancer initiation and …

Simple Summary Autophagy is a physiological process characterized by the degradation of
the cell components through lysosomes due to stimuli/stress. In this study, we review the …

Autophagy is an intracellular self-digestion mechanism, by which cellular components are
sorted into double-membrane autophagosomes and delivered to lysosomes for degradation …

Autophagy is a cellular degradation process in which portions of the cell's cytoplasm and
organelles are sequestered in a double-membrane bound vesicle called an …

In the last two decades, accumulating evidence pointed to the importance of autophagy in
various human diseases. As an essential evolutionary catabolic process of cytoplasmatic …

Autophagy is a cellular process to degrade long-lived or malfunctioning proteins and
obsolete or damaged organelles. It maintains cellular homeostasis and helps cells survive …