Autophagy is an evolutionarily conserved process whereby cytoplasm and cellular
organelles are degraded in lysosomes for amino acid and energy recycling. Autophagy is a …

Inhibiting cell survival and inducing cell death are the main approaches of tumor therapy.
Autophagy plays an important role on intracellular metabolic homeostasis by eliminating …

Macro‐autophagy is an ancient and highly conserved self‐degradative process that plays a
homeostatic role in normal cells by eliminating organelles, pathogens, and protein …

The tumor microenvironment (TME) is a complex environment where cancer cells reside and
interact with different types of cells, secreted factors, and the extracellular matrix …

Selective autophagy is critical for regulating cellular homeostasis by mediating lysosomal
turnover of a wide variety of substrates including proteins, aggregates, organelles, and …

Autophagy, the catabolic pathway in which cells recycle organelles and other parts of their
own cytoplasm, is increasingly recognised as an important cytoprotective mechanism in …

Autophagy is a lysosomal degradation pathway that can sequester cytosolic material,
including organelles, nonspecifically in a process called nonselective macroautophagy, or …

Autophagy sustains cellular homeostasis and metabolism in numerous diseases. By
regulating cancer metabolism, both tumor and microenvironmental autophagy promote …

Autophagy, as a type II programmed cell death, plays crucial roles with autophagy-related
(ATG) proteins in cancer. Up to now, the dual role of autophagy both in cancer progression …

Autophagy is a survival-promoting pathway that captures, degrades, and recycles
intracellular proteins and organelles in lysosomes. Autophagy preserves organelle function …