Due to the long latency period for solid tumor induction (median 12–13 years), the radiation-
induced malignancies now being observed are mostly related to the era of kilovoltage …

[en] The study of long-term effects of therapy for childhood cancer is important for several
reasons. An increasing proportion of children are now cured of their cancer and can expect …

Late effects of treatment for childhood cancer have become increasingly important as cure
rates improve. Until recently there has been only minimal awareness of late effects resulting …

The child appears more sensitive than the adult to the carcinogenic effects of radiation for
certain sites such as the breast and thyroid. However, there are few studies of persons who …

BACKGROUND Because ionizing radiation is a known carcinogen, diligent long‐term follow‐
up in children exposed to therapeutic radiation is required. The authors updated an earlier …

Elaine Ron association. They found strong linear dose–response relationships for all CNS
tumors combined and for glioma and meningioma separately. Moreover, they reported that …

Tissue complications of radiation therapy depend on the interplay of therapy, patient and
tumor factors. Acute local effects result from parenchymal cell hypoplasia. Chronic damage …

Previous reports of radiation‐related neoplasia have relied primarily upon patients treated
by orthovoltage to low doses for benign disease. This survey is believed to be the first to …

Objectives The majority of childhood cancer patients now achieve long-term survival, but the
treatments that cured their malignancy often put them at risk of adverse health outcomes …

Thirteen to 14 in 100,000 children will develop a malignancy by the time they are 15 years
old [23]. Due to dramatic improvements in survival over the past 20 years, about two thirds of …