[HTML][HTML] Iron accelerates Fusobacterium nucleatum–induced CCL8 expression in macrophages and is associated with colorectal cancer progression

T Yamane, Y Kanamori, H Sawayama, H Yano, A Nita… - JCI insight, 2022 - ncbi.nlm.nih.gov
Accumulating evidence suggests that high levels of Fusobacterium nucleatum in colorectal
tumor tissues can be associated with poor prognosis in patients with colorectal cancer …

Fusobacterium nucleatum promotes colorectal cancer metastasis through miR-1322/CCL20 axis and M2 polarization

C Xu, L Fan, Y Lin, W Shen, Y Qi, Y Zhang, Z Chen… - Gut …, 2021 - Taylor & Francis
Colorectal cancer (CRC) is one of the most common malignant tumors and is associated
with Fusobacterium nucleatum (F. nucleatum, Fn) infection. In this study, we explored the …

[HTML][HTML] Exploring the interplay between Fusobacterium nucleatum with the expression of microRNA, and inflammatory mediators in colorectal cancer

N Bostanghadiri, S Razavi, A Shariati… - Frontiers in …, 2023 - frontiersin.org
Background Fusobacterium nucleatum has been recognized as an important key bacterium
in the cause and spread of colorectal carcinogenesis. Nevertheless, the clinical relevance of …

Fusobacterium nucleatum and the Immune System in Colorectal Cancer

EM Borroni, D Qehajaj, FM Farina, D Yiu… - Current Colorectal …, 2019 - Springer
Abstract Purpose of Review To summarize the relationship between colorectal cancer
(CRC), immunity, and the gut microbiome, focusing on the population of Fusobacterium …

[HTML][HTML] Fusobacterium nucleatum Promotes the Progression of Colorectal Cancer Through Cdk5-Activated Wnt/β-Catenin Signaling

X Li, J Huang, T Yu, X Fang, L Lou, S Xin, L Ji… - Frontiers in …, 2021 - frontiersin.org
Background/Aims Growing evidence supports the direct link of Fusobacterium nucleatum
with colorectal cancer (CRC). However, to date, the underlying mechanism of action remains …

[HTML][HTML] Fusobacterium nucleatum and colorectal cancer: from phenomenon to mechanism

S Ou, H Wang, Y Tao, K Luo, J Ye, S Ran… - Frontiers in Cellular …, 2022 - frontiersin.org
Colorectal cancer (CRC) is the third most frequent malignant tumor. The gut microbiome acts
as a vital component of CRC etiology. Fusobacterium nucleatum (Fn) is a key member of …

[HTML][HTML] Fusobacterium nucleatum induces oxaliplatin resistance by inhibiting ferroptosis through E-cadherin/β-catenin/GPX4 axis in colorectal cancer

B Li, Z Wei, Z Wang, F Xu, J Yang, B Lin, Y Chen… - Free Radical Biology …, 2024 - Elsevier
Fusobacterium (F.) nucleatum is a carcinogenesis microbiota in colorectal cancer (CRC).
Growing evidence shows that F. nucleatum contributes to chemoresistance. Ferroptosis is …

The role of Fusobacterium nucleatum in colorectal cancer: from carcinogenesis to clinical management

CH Sun, BB Li, B Wang, J Zhao, XY Zhang… - Chronic diseases and …, 2019 - mednexus.org
Colorectal cancer (CRC) is a common malignant tumor that affects people worldwide.
Metagenomic analyses have shown an enrichment of Fusobacterium nucleatum (F …

[HTML][HTML] Relationship between Fusobacterium nucleatum, inflammatory mediators and microRNAs in colorectal carcinogenesis

MA Proença, JM Biselli, M Succi… - World journal of …, 2018 - ncbi.nlm.nih.gov
AIM To examine the effect of Fusobacterium nucleatum (F. nucleatum) on the
microenvironment of colonic neoplasms and the expression of inflammatory mediators and …

Clinical significance of Fusobacterium nucleatum, epithelial–mesenchymal transition, and cancer stem cell markers in stage III/IV colorectal cancer patients

X Yan, L Liu, H Li, H Qin, Z Sun - OncoTargets and therapy, 2017 - Taylor & Francis
Colorectal cancer (CRC) is a common digestive malignancy and emerging studies have
closely linked its initiation and development with gut microbiota changes. Fusobacterium …