Characterization of N6-Methyladenosine in Domesticated Yak Testes Before and After Sexual Maturity

X Wang, J Pei, S Guo, M Cao, P Bao… - Frontiers in Cell and …, 2021 - frontiersin.org
The potential regulatory role of N6-methyladenosine (m6A), the most prominent mRNA
modification in eukaryotes, has recently been identified in mammals, plants, and yeast …

Characterization of N6-methyladenosine in cattle-yak testis tissue

X Wang, J Pei, S Guo, M Cao, Y Kang… - Frontiers in Veterinary …, 2022 - frontiersin.org
N6-methyladenosine (m6A) is the most common form of eukaryotic mRNA modification, and
it has been shown to exhibit broad regulatory activity in yeast, plants, and mammals. The …

Transcriptome Studies Reveal the N6-Methyladenosine Differences in Testis of Yaks at Juvenile and Sexual Maturity Stages

S Guo, J Pei, X Wang, M Cao, L Xiong, Y Kang, Z Ding… - Animals, 2023 - mdpi.com
Simple Summary The methylation level of testicular tissue in young yaks and adult yaks was
determined, and the N 6-methyladenosine (m6A) level was significantly increased after …

Characterization of sexual maturity-associated N6-methyladenosine in boar testes

P Zhang, F Zhang, H Sui, X Yang, Y Ji, S Zheng, W Li… - BMC genomics, 2024 - Springer
Background The health and size of the testes are crucial for boar fertility. Testicular
development is tightly regulated by epigenetics. N6-methyladenosine (m6A) modification is …

[HTML][HTML] N6-Methyladenosine Modification-Related Genes Express Differentially in Sterile Male Cattle-Yaks

Y Liu, L Chen, H Jiang, H Wang, Y Zhang, Z Yuan… - Life, 2024 - mdpi.com
N6-methyladenosine (m6A), an RNA post-transcriptional modification, plays a crucial role in
spermatogenesis. Cattle-yaks are interspecific hybrid offsprings of yak and cattle, and male …

Transcriptome-Wide m6A analysis provides novel insights into testicular development and spermatogenesis in xia-nan cattle

S Liu, X Ma, T Yue, Z Wang, K Qi, J Li, F Lin… - Frontiers in Cell and …, 2021 - frontiersin.org
Testis is the primary organ of the male reproductive tract in mammals that plays a substantial
role in spermatogenesis. Improvement of our knowledge regarding the molecular …

Transcriptome-Wide Dynamics of m6A mRNA Methylation During Porcine Spermatogenesis

Z Liu, X Chen, P Zhang, F Li, L Zhang… - Genomics …, 2023 - academic.oup.com
Spermatogenesis is a continual process that occurs in the testes, in which diploid
spermatogonial stem cells (SSCs) differentiate and generate haploid spermatozoa. This …

The transcriptome-wide N6-methyladenosine (m6A) map profiling reveals the regulatory role of m6A in the yak ovary

S Guo, X Wang, M Cao, X Wu, L Xiong, P Bao, M Chu… - BMC genomics, 2022 - Springer
Background and aim Yak estrus is a seasonal phenomenon, probably involving epigenetic
regulation of synthesis and secretion of sex hormones as well as growth and development of …

The m6A methylation regulates gonadal sex differentiation in chicken embryo

J Li, X Zhang, X Wang, C Sun, J Zheng, J Li… - Journal of Animal …, 2022 - Springer
Background As a ubiquitous reversible epigenetic RNA modification, N6-methyladenosine
(m6A) plays crucial regulatory roles in multiple biological pathways. However, its functional …

Identification and functional annotation of m6A methylation modification in granulosa cells during antral follicle development in pigs

Z Cao, D Zhang, Y Wang, X Tong, LFC Avalos… - Animal reproduction …, 2020 - Elsevier
Abstract The N 6-methyladenosine (m6A) derivative has the capacity for ubiquitous
epigenetic modification of messenger RNA (mRNA) that regulates gene expression through …