Structural basis of DNA binding to human YB-1 cold shock domain regulated by phosphorylation

J Zhang, JS Fan, S Li, Y Yang, P Sun… - Nucleic acids …, 2020 - academic.oup.com
Human Y-box binding protein 1 (YB-1) is a multifunctional protein and overexpressed in
many types of cancer. It specifically recognizes DNA/RNA through a cold shock domain …

The pleiotropic functions of the Y‐box‐binding protein, YB‐1

K Kohno, H Izumi, T Uchiumi, M Ashizuka… - …, 2003 - Wiley Online Library
The Y‐box‐binding protein (YB‐1) represents the most evolutionary conserved nucleic‐acid‐
binding protein currently known. YB‐1 is a member of the cold‐shock domain (CSD) protein …

Thermodynamic characterization of the interaction between the human Y-box binding protein YB-1 and nucleic acids

Y Tanabe, S Nagatoishi, K Tsumoto - Molecular BioSystems, 2015 - pubs.rsc.org
Y-box binding protein 1 (YB-1) binds to both RNA and DNA to control transcription and
translation for the regulation of various cellular systems. YB-1 is overexpressed in some …

Crystal structure of a Y-box binding protein 1 (YB-1)–RNA complex reveals key features and residues interacting with RNA

XJ Yang, H Zhu, SR Mu, WJ Wei, X Yuan… - Journal of Biological …, 2019 - ASBMB
The Y-box binding protein 1 (YB-1) is a member of the cold shock domain (CSD) protein
family and is recognized as an oncogenic factor in several solid tumors. By binding to RNA …

Y box binding protein 1 (YB-1) oncoprotein at the hub of DNA proliferation, damage and cancer progression

F Sangermano, A Delicato, V Calabrò - Biochimie, 2020 - Elsevier
The Y Box binding protein 1 (YB-1) belongs to the highly conserved Cold Shock Domain
protein family and is a major component of messenger ribonucleoprotein particles (mRNPs) …

The solution structure and DNA-binding properties of the cold-shock domain of the human Y-box protein YB-1

CPAM Kloks, CAEM Spronk, E Lasonder… - Journal of molecular …, 2002 - Elsevier
The human Y-box protein 1 (YB-1) is a member of the Y-box protein family, a class of
proteins involved in transcriptional and translational regulation of a wide range of genes …

YB‐1 protein: functions and regulation

DN Lyabin, IA Eliseeva… - Wiley Interdisciplinary …, 2014 - Wiley Online Library
The Y‐box binding protein 1 (YB‐1, YBX1) is a member of the family of DNA‐and RNA‐
binding proteins with an evolutionarily ancient and conserved cold shock domain. It falls into …

A comprehensive review of the functions of YB-1 in cancer stemness, metastasis and drug resistance

A Alkrekshi, W Wang, PS Rana, V Markovic… - Cellular signalling, 2021 - Elsevier
The Y Box binding protein 1 (YB-1) is a member of the highly conserved Cold Shock Domain
protein family with multifunctional properties both in the cytoplasm and inside the nucleus …

[HTML][HTML] Significance of the Y-box proteins in human cancers

K Matsumoto, BH Bay - Journal of molecular and genetic medicine …, 2005 - ncbi.nlm.nih.gov
Y-box proteins belong to the cold shock domain family of proteins that are known to be
involved in both transcriptional and translational control. Here, we give a brief overview of …

YB-1 as an oncoprotein: functions, regulation, post-translational modifications, and targeted therapy

Q Yin, M Zheng, Q Luo, D Jiang, H Zhang, C Chen - Cells, 2022 - mdpi.com
Y box binding protein 1 (YB-1) is a protein with a highly conserved cold shock domain (CSD)
that also belongs to the family of DNA-and RNA-binding proteins. YB-1 is present in both the …